Contact

Maria Holzapfel
Maria Holzapfel
Research Technician
Phone: +49 (0) 89-30622-256

Viral Vectors

Mode of action of a viral vector used for gene therapy. Zoom Image
Mode of action of a viral vector used for gene therapy.
AAV Virus for miRNA overexpression in neurons Zoom Image
AAV Virus for miRNA overexpression in neurons

Virus Production

Understanding and research on many ailments are nowadays based on a genetic level. Through the use of viral vectors, we came closer to the goal of mastering diseases by controlled genetic manipulation. Viral vectors are also used to explore various diseases because they allow us to monitor genes in their functionality and exert influence on them. Over-expression, correction, blockage or even the destruction of a target gene are just some of the possibilities that can be created by using these vectors. The route of delivery, cell tropism, the size of the transgene and possible side effects are only some of the factors that must be considered when selecting the appropriate viral vector for the respective application.

Services:

  • Designing of the viral plasmids
  • Production of lentiviral and adeno-associated viral vectors
  • Room and machines available for injection of the viruses and habituation of the mice after treatment in compliance with S2 regulations
 
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