Childhood maltreatment leaves long-lasting modifications on genes
Research report (imported) 2013 - Max Planck Institute of Psychiatry
Childhood maltreatment not only harms mind and body but leaves long-lasting modifications on genes. Patients suffering from posttraumatic stress disorder who have or have not experienced childhood maltreatment, displayed distinct epigenetic profiles in immune cells. Thus identical psychiatric diagnosis can be accompanied by distinct biological signatures and possibly differential response to treatment. This highlights the importance of the patient’s individual biography in defining disease subtypes.