Publications of Nikolaos Koutsouleris

Mena, S.; Coutts, F.; von Trott, J.; Ucur, E.; Vetter, C.; Kahn, R. R.; Fleischhacker, W. W.; Kane, J. M.; Howes, O. D.; Upthegrove, R. et al.; Lalousis, P. A.; Koutsouleris, N.: AI-based prediction of depression symptomatology in first-episode psychosis patients: insights from the EUFEST and RAISE-ETP clinical trials. PSYCHOLOGICAL MEDICINE 55, e221 (2025)

Lange, M.; Gogarty, E.; Martyn, M.; Braude, P.; Fayez, F.; Koutsouleris, N.; Howes, O.; Twumasi, R.; Carter, B.: An accessible, timely method for identifying medications for repurposing: hypothesis generating; testing and validation. BMC DIGITAL HEALTH 3 (1), 30 (2025)

Arribas, M.; Barnby, J. M.; Patel, R.; Mccutcheon, R. A.; Kornblum, D.; Shetty, H.; Krakowski, K.; Stahl, D.; Koutsouleris, N.; Mcguire, P. et al.; Fusar-Poli, P.; Oliver, D.: Longitudinal evolution of the transdiagnostic prodrome to severe mental disorders: a dynamic temporal network analysis informed by natural language processing and electronic health records. MOLECULAR PSYCHIATRY (2025)

Bienek, O.; Allott, K.; Antonucci, L.; Bertolino, A.; Bonivento, C.; Borgwardt, S.; Brambilla, P.; Chisholm, K.; Dannlowski, U.; Lichtenstein, T. K. et al.; Kambeitz, J.; Kambeitz-Ilankovic, L.; Koutsouleris, N.; Lencer, R.; Griffiths, S. L.; Maggioni, E.; Meisenzahl, E.; Pantelis, C.; Rosen, M.; Ruhrmann, S.; Salokangas, R. K. R.; Stainton, A.; Surmann, M.; Upthegrove, R.; Wenzel, J.; Wood, S. J.; Romer, G.; Mueller, J. M.: Neurocognitive dysfunction in adolescents with recent onset major depressive disorder: a cross-sectional comparative study. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY 34 (6), pp. 1873 - 1882 (2025)

Blackman, G.; Byrne, R.; Gill, N.; Fanshawe, J. B.; Bell, V.; Watson, C.; Koutsouleris, N.; Fusar-Poli, P.; Pollak, T. A.; McGuire, P.: How common is secondary psychosis? Estimates from a systematic review and meta-analysis. World psychiatry: official journal of the World Psychiatric Association (WPA) 24 (1), pp. 145 - 146 (2025)

Buciuman, M.-O.; Haas, S. S.; Antonucci, L. A.; Sarisik, E.; Khuntia, A.; Lichtenstein, T.; Rosen, M.; Kambeitz, J.; Pantelis, C.; Lencer, R. et al.; Bertolino, A.; Brambilla, P.; Upthegrove, R.; Wood, S. J.; Falkai, P.; Riecher-Rossler, A.; Ruhrmann, S.; Schultze-Lutter, F.; Meisenzahl, E.; Hietala, J.; Salokangas, R. K. R.; Borgwardt, S.; Dwyer, D. B.; Kambeitz-Ilankovic, L.; Koutsouleris, N.: From Snapshots to Stable Outcomes: rs-fMRI-based Prognosis of Functioning in Patients with Psychosis Risk or Recent-Onset Depression. Biological psychiatry (2025)

Eder, J.; Dong, M. S.; Woehler, M.; Simon, M. S.; Glocker, C.; Pfeiffer, L.; Gaus, R.; Wolf, J.; Mestan, K.; Krcmar, H. et al.; Koutsouleris, N.; Schneider, A.; Gensichen, J.; Musil, R.; Falkai, P.; POKAL, G.: A multimodal approach to depression diagnosis: insights from machine learning algorithm development in primary care. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2025)

Fazio, L.; Stolfa, G.; Passiatore, R.; Tavella, A.; Blasi, G.; Buciuman, M. O.; Goldman, A. L.; Haas, S. S.; Kambeitz-Ilankovic, L.; Koutsouleris, N. et al.; Nicoli, M.; Popolizio, T.; Rampino, A.; Ruef, A.; Sambataro, F.; Selvaggi, P.; Ulrich, W.; Weinberger, D. R.; Bertolino, A.; Antonucci, L. A.; Pergola, G.: Altered Brain-Behavior Association During Resting State is a Potential Psychosis Risk Marker. ADVANCED SCIENCE (2025)

Khuntia, A.; Buciuman, M.-O.; Fanning, J. M.; Stolicyn, A.; Vetter, C.; Armio, R.-L.; From, T.; Goffi, F.; Hahn, L.; Kaufmann, T. et al.; Laurikainen, H.; Maggioni, E.; Martinez-Zalacain, I.; Ruef, A.; Dong, M. S.; Schwarz, E.; Squarcina, L.; Andreassen, O.; Bellani, M.; Brambilla, P.; Haren, N. v.; Hietala, J.; Lawrie, S. M.; Soriano-Mas, C.; Whalley, H.; Taquet, M.; Meisenzahl, E.; Falkai, P.; Wiegand, A.; Koutsouleris, N.: Towards collaborative data science in mental health research: The ECNP neuroimaging network accessible data repository. Neuroscience applied 4, 105407 (2025)

Richter, M.; Emden, D.; Leenings, R.; Winter, N. R.; Mikolajczyk, R.; Massag, J.; Zwiky, E.; Borgers, T.; Redlich, R.; Koutsouleris, N. et al.; Falguera, R.; Edwin Thanarajah, S.; Padberg, F.; Reinhard, M. A.; Back, M. D.; Morina, N.; Buhlmann, U.; Kircher, T.; Dannlowski, U.; Hahn, T.; Opel, N.: Generalizability of clinical prediction models in mental health. MOLECULAR PSYCHIATRY (2025)

Sarisik, E.; Popovic, D.; Keeser, D.; Khuntia, A.; Schiltz , K.; Falkai, P.; Pogarell, O.; Koutsouleris, N.: EEG-based Signatures of Schizophrenia, Depression, and Aberrant Aging: A Supervised Machine Learning Investigation. SCHIZOPHRENIA BULLETIN 51 (3), pp. 804 - 817 (2025)

Schoenweger, P.; Eder, J.; Pfeiffer, L.; Falkai, P.; Kirschneck, M.; Simon, M. S.; Ditzen-Janotta, C.; Brunoni, A. R.; Coenen, M.; Dong, M. S. et al.; Gensichen, J.; Glocker, C.; Koutsouleris, N.; Musil, R.; Schmitt, A.; Jung-Sievers, C.: Measuring social environment factors of inpatients and outpatients with depression in Germany: a cross-sectional study. BMJ mental health 28 (1) (2025)

Vetter, C. S.; Bender, A.; Dwyer, D. B.; Montembeault, M.; Ruef, A.; Chisholm, K.; Kambeitz-Ilankovic, L.; Antonucci, L. A.; Ruhrmann, S.; Kambeitz, J. et al.; Rosen, M.; Lichtenstein, T.; Riecher-Rossler, A.; Upthegrove, R.; Salokangas, R. K. R.; Hietala, J.; Pantelis, C.; Lencer, R.; Meisenzahl, E.; Wood, S. J.; Brambilla, P.; Borgwardt, S.; Falkai, P.; Bertolino, A.; Koutsouleris, N.: Exploring the predictive value of structural covariance networks for the diagnosis of schizophrenia. Frontiers in psychiatry 16, 1570797 (2025)

Arribas, M.; Oliver, D.; Patel, R.; Kornblum, D.; Shetty, H.; Damiani, S.; Krakowski, K.; Provenzani, U.; Stahl, D.; Koutsouleris, N. et al.; McGuire, P.; Fusar-Poli, P.: A transdiagnostic prodrome for severe mental disorders: an electronic health record study. MOLECULAR PSYCHIATRY (2024)

Dong, M. S.; Rokicki, J.; Dwyer, D.; Papiol, S.; Streit, F.; Rietschel, M.; Wobrock, T.; Mueller-Myhsok, B.; Falkai, P.; Westlye, L. T. et al.; Andreassen, O. A.; Palaniyappan, L.; Schneider-Axmann, T.; Hasan, A.; Schwarz, E.; Koutsouleris, N.: Multimodal workflows optimally predict response to repetitive transcranial magnetic stimulation in patients with schizophrenia: a multisite machine learning analysis. TRANSLATIONAL PSYCHIATRY 14 (1), 196 (2024)

Falkai, P.; Koutsouleris, N.: Why is it so difficult to implement precision psychiatry into clinical care? LANCET REGIONAL HEALTH-EUROPE 43, 100952 (2024)

Koehler, J. C.; Dong, M. S.; Bierlich, A. M.; Fischer, S.; Spaeth, J.; Plank, I. S.; Koutsouleris, N.; Falter-Wagner, C. M.: Machine learning classification of autism spectrum disorder based on reciprocity in naturalistic social interactions. TRANSLATIONAL PSYCHIATRY 14 (1), 76 (2024)

Koehler, J. C.; Dong, M. S.; Song, D.-Y.; Bong, G.; Koutsouleris, N.; Yoo, H.; Falter-Wagner, C. M.: Classifying autism in a clinical population based on motion synchrony: a proof-of-concept study using real-life diagnostic interviews. SCIENTIFIC REPORTS 14 (1), 5663 (2024)

Korda, A. I.; Andreou, C.; Ruef, A.; Hahn, L.; Schmidt, A.; Dannlowski, U.; Kambeitz-Ilankovic, L.; Dwyer, D. B.; Kambeitz, J.; Wenzel, J. et al.; Ruhrmann, S.; Wood, S. J.; Salokangas, R. K. R.; Pantelis, C.; Schultze-Lutter, F.; Meisenzahl, E.; Brambilla, P.; Selvaggi, P.; Bertolino, A.; Hietala, J.; Upthegrove, R.; Lalousis, P. A.; Riecher-Roessler, A.; Davatzikos, C.; Lencer, R.; Koutsouleris, N.; Borgwardt, S.; PRONIA, C.: Brain texture as a marker of transdiagnostic clinical profiles in patients with recent-onset psychosis and depression. NATURE MENTAL HEALTH 2, pp. 76 - 87 (2024)

Meyhoefer, I.; Sprenger, A.; Derad, D.; Grotegerd, D.; Leenings, R.; Leehr, E. J.; Breuer, F.; Surmann, M.; Rolfes, K.; Arolt, V. et al.; Romer, G.; Lappe, M.; Rehder, J.; Koutsouleris, N.; Borgwardt, S.; Schultze-Lutter, F.; Meisenzahl, E.; Kircher, T. T. J.; Keedy, S. S.; Bishop, J. R.; Ivleva, E. I.; McDowell, J. E.; Reilly, J. L.; Hill, S. K.; Pearlson, G. D.; Tamminga, C. A.; Keshavan, M. S.; Gershon, E. S.; Clementz, B. A.; Sweeney, J. A.; Hahn, T.; Dannlowski, U.; Lencer, R.: Evidence from comprehensive independent validation studies for smooth pursuit dysfunction as a sensorimotor biomarker for psychosis. SCIENTIFIC REPORTS 14 (1), 13859 (2024)