Special Outpatient Clinic for Patients with Neuropsychiatric Post-COVID- and ME/CFS-Symptoms

June 17, 2026

After recovering from COVID-19, neurological and psychiatric symptoms such as headaches, difficulty concentrating, depression, anxiety, or sleep disturbances may persist or develop. Some patients also experience ME/CFS-like symptoms, such as persistent fatigue.

Post-COVID syndrome refers to the course of symptoms in patients who, after recovering from a coronavirus infection, continue to experience (in some cases new) symptoms beyond the 12th week. These often include neuropsychiatric symptoms: cognitive impairments, sometimes combined with headaches or muscle tremors, depression, anxiety, or sleep disturbances. COVID-19 can affect the brain both through the infection itself and through the inflammatory response (encephalitis) or processes triggered by it (encephalopathy).

Infection with the coronavirus can also lead to neurological and psychiatric symptoms; if these symptoms persist beyond the acute phase of the illness or appear only afterward, the condition is referred to as post-COVID.© Pixabay_Pabliyo — Infection with the coronavirus can also lead to neurological and psychiatric symptoms; if these symptoms persist beyond the acute phase of the illness or appear only afterward, the condition is referred to as post-COVID. © Pixabay_Pabliyo

Infection with the coronavirus can also lead to neurological and psychiatric symptoms; if these symptoms persist beyond the acute phase of the illness or appear only afterward, the condition is referred to as post-COVID.
© Pixabay_Pabliyo

ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) is a separate neuroimmunological condition that shares many symptoms with post-COVID syndrome, including severe physical and mental exhaustion, body aches, and difficulty concentrating. While post-COVID describes persistent symptoms following a COVID-19 infection, ME/CFS can be triggered by various infections.

At the Max Planck Research Hospital, the focus is on neuropsychiatric outpatient treatment for both conditions. Neurologists and psychiatrists draw on their expertise from the outpatient clinic for inflammatory CNS disorders/MS outpatient clinic, the sleep clinic, and psychiatry as a whole.

The first priority is the diagnosis and differential diagnosis of the symptoms, followed by symptomatic therapy based on the specific clinical presentation. For diagnosis, the clinic primarily utilizes neuropsychology, MRI, cerebrospinal fluid analysis, and neurophysiology.

Focus on young patients with accompanying depressive symptoms

Services for young patients

Our outpatient clinic is a partner of the Munich Chronic Fatigue Center for Young People (MCFC). The Center specializes in the treatment of chronic fatigue, post-acute infection and vaccination syndromes (PAIVS), and ME/CFS in young adults. Patients between the ages of 18 and 29 can register directly with the MCFC and will then be referred to one of the partner clinics in Munich. Details on registration can be found in the column on the left.

Services for patients with depressive symptoms

Post-COVID can also lead to mental health issues such as depressive mood, concentration problems, low motivation, lack of energy, sleep disturbances, anxiety, etc. If you have developed these symptoms in connection with a COVID-19 infection, we invite you to participate in our IMPACT-D+ study. In this study, we are investigating the effectiveness of repetitive transcranial magnetic stimulation (rTMS) for depressive symptoms associated with COVID-19. rTMS is a safe, non-invasive procedure that is already being used successfully to treat depression, especially when medication alone is not sufficient. You can find all information about the study and how to participate here (in German).