Publications of Nils C. Gassen
All genres
Journal Article (41)
2023
Journal Article
145 (4), pp. 439 - 459 (2023)
Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. ACTA NEUROPATHOLOGICA 2022
Journal Article
Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity. MOLECULAR PSYCHIATRY (2022)
Journal Article
8 (10), eabi4797 (2022)
Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism. SCIENCE ADVANCES
Journal Article
41 (10), 111766 (2022)
Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning. CELL REPORTS 2021
Journal Article
The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. MOLECULAR PSYCHIATRY (2021)
Journal Article
13, 731603 (2021)
Myo-Inositol Levels in the Dorsal Hippocampus Serve as Glial Prognostic Marker of Mild Cognitive Impairment in Mice. FRONTIERS IN AGING NEUROSCIENCE
Journal Article
15, 100401 (2021)
Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans. NEUROBIOLOGY OF STRESS
Journal Article
12 (1), 4643 (2021)
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion. NATURE COMMUNICATIONS
Journal Article
479, pp. 91 - 106 (2021)
Brain Expression, Physiological Regulation and Role in Motivation and Associative Learning of Peroxisome Proliferator-activated Receptor y. NEUROSCIENCE
Journal Article
53 (2), pp. 390 - 401 (2021)
Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons. EUROPEAN JOURNAL OF NEUROSCIENCE 2020
Journal Article
228 (2), e13345 (2020)
Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus. ACTA PHYSIOLOGICA 2019
Journal Article
10, 5770 (2019)
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. NATURE COMMUNICATIONS
Journal Article
116 (23), pp. 11370 - 11379 (2019)
Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2018
Journal Article
91, pp. 149 - 158 (2018)
Temporal profiling of an acute stress-induced behavioral phenotype in mice and role of hippocampal DRR1. PSYCHONEUROENDOCRINOLOGY 2017
Journal Article
74 (Part B SI), pp. 356 - 365 (2017)
Life stress, glucocorticoid signaling, and the aging epigenome: Implications for aging-related diseases. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
Journal Article
8, 1725 (2017)
Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function. NATURE COMMUNICATIONS
Journal Article
18 (12), 2614 (2017)
The FKBP51 Glucocorticoid Receptor Co-Chaperone: Regulation, Function, and Implications in Health and Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2016
Journal Article
80 (10), pp. 743 - 753 (2016)
Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction. BIOLOGICAL PSYCHIATRY
Journal Article
6, 35317 (2016)
Purine and pyrimidine metabolism: Convergent evidence on chronic antidepressant treatment response in mice and humans. SCIENTIFIC REPORTS
Journal Article
23 (10), pp. 1579 - 1591 (2016)
The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51. CELL DEATH AND DIFFERENTIATION