Publications of Felix Hausch
All genres
Journal Article (59)
2020
Journal Article
11 (1), 5621 (2020)
Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly. NATURE COMMUNICATIONS
Journal Article
25 (3), e12758 (2020)
The selective FKBP51 inhibitor SAFit2 reduces alcohol consumption and reinstatement of conditioned alcohol effects in mice. ADDICTION BIOLOGY 2019
Journal Article
58 (28), pp. 9429 - 9433 (2019)
Selective Inhibitors of FKBP51 Employ Conformational Selection of Dynamic Invisible States. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2018
Journal Article
159 (7), pp. 1224 - 1234 (2018)
The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes. PAIN
Journal Article
12, 262 (2018)
Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs. FRONTIERS IN BEHAVIORAL NEUROSCIENCE 2017
Journal Article
7 (1), 613 (2017)
The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells. SCIENTIFIC REPORTS 2016
Journal Article
59 (6), pp. 2410 - 2422 (2016)
Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51. JOURNAL OF MEDICINAL CHEMISTRY
Journal Article
11 (2), e0148608 (2016)
Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores. PLOS ONE
Journal Article
8 (325), 325ra19 (2016)
The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling. SCIENCE TRANSLATIONAL MEDICINE 2015
Journal Article
58 (19), pp. 7796 - 7806 (2015)
Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands. JOURNAL OF MEDICINAL CHEMISTRY
Journal Article
1850 (10 (Special Issue)), pp. 2035 - 2040 (2015)
FKBPs and their role in neuronal signaling. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Journal Article
43 (14), pp. 6983 - 6993 (2015)
FKBP51 employs both scaffold and isomerase functions to promote NF-kappa B activation in melanoma. NUCLEIC ACIDS RESEARCH
Journal Article
55, pp. 128 - 143 (2015)
Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice. PSYCHONEUROENDOCRINOLOGY
Journal Article
35 (17), pp. 6639 - 6653 (2015)
Orexin-Corticotropin-Releasing Factor Receptor Heteromers in the Ventral Tegmental Area as Targets for Cocaine. JOURNAL OF NEUROSCIENCE
Journal Article
21 (3), pp. 276 - 280 (2015)
A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease. NATURE MEDICINE
Journal Article
54 (1), pp. 345 - 348 (2015)
Rational Design and Asymmetric Synthesis of Potent and Neurotrophic Ligands for FK506-Binding Proteins (FKBPs). ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Journal Article
11 (1), pp. 33 - + (2015)
Selective inhibitors of the FK506-binding protein 51 by induced fit. NATURE CHEMICAL BIOLOGY
Journal Article
35 (24), pp. 9007 - 16 (2015)
Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties. The Journal of neuroscience: the official journal of the Society for Neuroscience 2014
Journal Article
57 (22), pp. 9473 - 9479 (2014)
Loratadine and Analogues: Discovery and Preliminary Structure-Activity Relationship of Inhibitors of the Amino Acid Transporter B(0)AT2. JOURNAL OF MEDICINAL CHEMISTRY
Journal Article
16 (20), pp. 5254 - 5257 (2014)
Stereoselective Construction of the 5-Hydroxy Diazabicyclo[4.3.1]decane-2-one Scaffold, a Privileged Motif for FK506-Binding Proteins. ORGANIC LETTERS