Publications of Felix Hausch

Jagtap, P. K. A.; Kubelka, T.; Soni, K.; Will, C. L.; Garg, D.; Sippel, C.; Kapp, T. G.; Potukuchi, H. K.; Schorpp, K.; Hadian, K. et al.; Kessler, H.; Luehrmann, R.; Hausch, F.; Bach, T.; Sattler, M.: Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly. NATURE COMMUNICATIONS 11 (1), 5621 (2020)

Koenig, L.; Kalinichenko, L. S.; Huber, S. E.; Voll, A. M.; Bauder, M.; Kornhuber, J.; Hausch, F.; Mueller, C. P.: The selective FKBP51 inhibitor SAFit2 reduces alcohol consumption and reinstatement of conditioned alcohol effects in mice. ADDICTION BIOLOGY 25 (3), e12758 (2020)

Jagtap, P. K. A.; Asami, S.; Sippel, C.; Kaila, V. R. I.; Hausch, F.; Sattler, M.: Selective Inhibitors of FKBP51 Employ Conformational Selection of Dynamic Invisible States. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 58 (28), pp. 9429 - 9433 (2019)

Maiaru, M.; Morgan, O. B.; Mao, T.; Breitsamer, M.; Bamber, H.; Pöhlmann, M.; Schmidt, M. V.; Winter, G.; Hausch, F.; Geranton, S. M.: The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes. PAIN 159 (7), pp. 1224 - 1234 (2018)

Pöhlmann, M. L.; Häusl, A. S.; Harbich, D.; Balsevich, G.; Engelhardt, C.; Feng, X.; Breitsamer, M.; Hausch, F.; Winter, G.; Schmidt, M. V.: Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs. FRONTIERS IN BEHAVIORAL NEUROSCIENCE 12, 262 (2018)

Schuster, M.; Schnell, L.; Feigl, P.; Birkhofer, C.; Mohr, K.; Roeder, M.; Carle, S.; Langer, S.; Tippel, F.; Buchner, J. et al.; Fischer, G.; Hausch, F.; Frick, M.; Schwan, C.; Aktories, K.; Schiene-Fischer, C.; Barth, H.: The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells. SCIENTIFIC REPORTS 7 (1), 613 (2017)

Gaali, S.; Feng, X.; Hähle, A.; Sippel, C.; Bracher, A.; Hausch, F.: Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51. JOURNAL OF MEDICINAL CHEMISTRY 59 (6), pp. 2410 - 2422 (2016)

Kirmeier, T.; Gopalakrishnan, R.; Ganal, V.; Werner, A. M.; Cuboni, S.; Rudolf, G. C.; Hoefner, G.; Wanner, K. T.; Sieber, S. A.; Schmidt, U. et al.; Holsboer, F.; Rein, T.; Hausch, F.: Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores. PLOS ONE 11 (2), e0148608 (2016)

Maiaru, M.; Tochiki, K. K.; Cox, M. B.; Annan, L. V.; Bell, C. G.; Feng, X.; Hausch, F.; Geranton, S. M.: The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling. SCIENCE TRANSLATIONAL MEDICINE 8 (325), 325ra19 (2016)

Feng, X.; Sippel, C.; Bracher, A.; Hausch, F.: Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands. JOURNAL OF MEDICINAL CHEMISTRY 58 (19), pp. 7796 - 7806 (2015)

Hausch, F.: FKBPs and their role in neuronal signaling. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1850 (10 (Special Issue)), pp. 2035 - 2040 (2015)

Romano, S.; Xiao, Y.; Nakaya, M.; D'Angelillo, A.; Chang, M.; Jin, J.; Hausch, F.; Masullo, M.; Feng, X.; Romano, M. F. et al.; Sun, S.-C.: FKBP51 employs both scaffold and isomerase functions to promote NF-kappa B activation in melanoma. NUCLEIC ACIDS RESEARCH 43 (14), pp. 6983 - 6993 (2015)

Kohl, C.; Wang, X.-D.; Grosse, J.; Fournier, C.; Harbich, D.; Westerholz, S.; Li, J.-T.; Bacq, A.; Sippel, C.; Hausch, F. et al.; Sandi, C.; Schmidt, M. V.: Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice. PSYCHONEUROENDOCRINOLOGY 55, pp. 128 - 143 (2015)

Navarro, G.; Quiroz, C.; Moreno-Delgado, D.; Sierakowiak, A.; McDowell, K.; Moreno, E.; Rea, W.; Cai, N.-S.; Aguinaga, D.; Howell, L. A. et al.; Hausch, F.; Cortes, A.; Mallol, J.; Casado, V.; Lluis, C.; Canela, E. I.; Ferre, S.; McCormick, P. J.: Orexin-Corticotropin-Releasing Factor Receptor Heteromers in the Ventral Tegmental Area as Targets for Cocaine. JOURNAL OF NEUROSCIENCE 35 (17), pp. 6639 - 6653 (2015)

Riebold, M.; Kozany, C.; Freiburger, L.; Sattler, M.; Buchfelder, M.; Hausch, F.; Stalla, G. K.; Páez-Pereda, M.: A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease. NATURE MEDICINE 21 (3), pp. 276 - 280 (2015)

Pomplun, S.; Wang, Y.; Kirschner, A.; Kozany, C.; Bracher, A.; Hausch, F.: Rational Design and Asymmetric Synthesis of Potent and Neurotrophic Ligands for FK506-Binding Proteins (FKBPs). ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 54 (1), pp. 345 - 348 (2015)

Gaali, S.; Kirschner, A.; Cuboni, S.; Hartmann, J.; Kozany, C.; Balsevich, G.; Namendorf, C.; Fernandez-Vizarra, P.; Sippel, C.; Zannas, A. S. et al.; Draenert, R.; Binder, E. B.; Almeida, O. F. X.; Ruehter, G.; Uhr, M.; Schmidt, M. V.; Touma, C.; Bracher, A.; Hausch, F.: Selective inhibitors of the FK506-binding protein 51 by induced fit. NATURE CHEMICAL BIOLOGY 11 (1), pp. 33 - + (2015)

Hartmann, J.; Wagner, K. V.; Gaali, S.; Kirschner, A.; Kozany, C.; Ruhter, G.; Dedic, N.; Häusl, A. S.; Hoeijmakers, L.; Westerholz, S. et al.; Namendorf, C.; Gerlach, T.; Uhr, M.; Chen, A.; Deussing, J. M.; Holsboer, F.; Hausch, F.; Schmidt, M. V.: Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties. The Journal of neuroscience: the official journal of the Society for Neuroscience 35 (24), pp. 9007 - 16 (2015)

Cuboni, S.; Devigny, C.; Hoogeland, B.; Strasser, A.; Pomplun, S.; Hauger, B.; Hoefner, G.; Wanner, K. T.; Eder, M.; Buschauer, A. et al.; Holsboer, F.; Hausch, F.: Loratadine and Analogues: Discovery and Preliminary Structure-Activity Relationship of Inhibitors of the Amino Acid Transporter B(0)AT2. JOURNAL OF MEDICINAL CHEMISTRY 57 (22), pp. 9473 - 9479 (2014)

Bischoff, M.; Sippel, C.; Bracher, A.; Hausch, F.: Stereoselective Construction of the 5-Hydroxy Diazabicyclo[4.3.1]decane-2-one Scaffold, a Privileged Motif for FK506-Binding Proteins. ORGANIC LETTERS 16 (20), pp. 5254 - 5257 (2014)