Publications of Mathias V. Schmidt

Kovarova, V.; Bordes, J.; Mitra, S.; Narayan, S.; Springer, M.; Brix, L.; Deussing, J. M.; Schmidt, M. V.: Deep phenotyping reveals CRH and FKBP51-dependent behavioral profiles following chronic social stress exposure in male mice. NEUROPSYCHOPHARMACOLOGY 50 (3), pp. 556 - 567 (2025)

van Doeselaar, L.; Abromeit, A.; Stark, T.; Menegaz, D.; Ballmann, M.; Mitra, S.; Yang, H.; Rehawi, G.; Huettl, R. E.; Bordes, J. et al.; Narayan, S.; Harbich, D.; Deussing, J. M.; Rammes, G.; Czisch, M.; Knauer-Arloth, J.; Eder, M.; Lopez, J. P.; Schmidt, M. V.: FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice. Nature communications 16 (1), 2529 (2025)

Bordes, J.; Bajaj, T.; Miranda, L.; van Doeselaar, L.; Brix, L.; Narayan, S.; Yang, H.; Mitra, S.; Kovarova, V.; Springer, M. et al.; Kleigrewe, K.; Müller-Myhsok, B.; Gassen, N. C.; Schmidt, M. V.: Sex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism. COMMUNICATIONS BIOLOGY 7 (1), 1684 (2024)

Contreras, R. E.; Gruber, T.; Gonzalez-Garcia, I.; Schriever, S. C.; De Angelis, M.; Mallet, N.; Bernecker, M.; Legutko, B.; Kabra, D.; Schmidt, M. et al.; Tschoep, M. H.; Gutierrez-Aguilar, R.; Mellor, J.; Garcia-Caceres, C.; Pfluger, P. T.: HDAC5 controls a hypothalamic STAT5b-TH axis, the sympathetic activation of ATP-consuming futile cycles and adult-onset obesity in male mice. MOLECULAR METABOLISM 90, 102033 (2024)

Hartmann, J.; Bajaj, T.; Otten, J.; Klengel, C.; Ebert, T.; Gellner, A.-K.; Junglas, E.; Hafner, K.; Anderzhanova, E. A.; Tang, F. et al.; Missig, G.; Rexrode, L.; Trussell, D. T.; Li, K. X.; Pohlmann, M. L.; Mackert, S.; Geiger, T. M.; Heinz, D. E.; Lardenoije, R.; Dedic, N.; McCullough, K. M.; Prochnicki, T.; Rhomberg, T.; Martinelli, S.; Payton, A.; Robinson, A. C.; Stein, V.; Latz, E.; Carlezon Jr., W. A.; Hausch, F.; Schmidt, M. V.; Murgatroyd, C.; Berretta, S.; Klengel, T.; Pantazopoulos, H.; Ressler, K. J.; Gassen, N. C.: SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration. NATURE COMMUNICATIONS 15 (1), 2635 (2024)

Mitra, S.; Kumar, G. S. S.; Samanta, A.; Schmidt, M. V.; Thakur, S. S.: Hypothalamic protein profiling from mice subjected to social defeat stress. MOLECULAR BRAIN 17 (1), 30 (2024)

Stepan, J.; Heinz, D. E.; Dethloff, F.; Wiechmann , S.; Martinelli, S.; Hafner, K.; Ebert, T.; Junglas, E.; Haeusl, A. S.; Poehlmann, M. L. et al.; Jakovcevski, M.; Pape, J. C.; Zannas, A. S.; Bajaj , T.; Hermann, A.; Ma, X.; Pavenstaedt, H.; Schmidt, M. V.; Philipsen, A.; Turck, C. W.; Deussing, J. M.; Rammes, G.; Robinson, A. C.; Payton, A.; Wehr, M. C.; Stein, V.; Murgatroyd, C.; Kremerskothen, J.; Kuster, B.; Wotjak, C. T.; Gassen, N. C.: Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice. SCIENCE SIGNALING 17 (834), eadj6603 (2024)

Brix, L.; Monleon, D.; Collado, M. C.; Ederveen, T. H. A.; Toksoez, I.; Bordes, J.; van Doeselaar, L.; Engelhardt, C.; Mitra, S.; Narayan, S. et al.; Schmidt, M. V.: Metabolic effects of early life stress and pre-pregnancy obesity are long lasting and sex specific in mice. EUROPEAN JOURNAL OF NEUROSCIENCE (2023)

Bordes, J.; Miranda, L.; Mueller-Myhsok, B.; Schmidt, M. V.: Advancing social behavioral neuroscience by integrating ethology and comparative psychology methods through machine learning. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 151, 105243 (2023)

Bordes, J.; Miranda, L.; Reinhardt, M.; Narayan, S.; Hartmann, J.; Newman, E. L.; Brix, L.; van Doeselaar, L.; Engelhardt, C.; Dillmann, L. et al.; Mitra, S.; Ressler, K. J.; Puetz, B.; Agakov, F.; Mueller-Myhsok, B.; Schmidt, M. V.: Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress. NATURE COMMUNICATIONS 14 (1), 4319 (2023)

Brivio, E.; Kos, A.; Ulivi, A. F.; Karamihalev, S.; Reßle, A.; Stoffel, R.; Hirsch, D.; Stelzer, G.; Schmidt, M. V.; Lopez, J. P. et al.; Chen, A.: Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus. CELL REPORTS 42 (8), 112874 (2023)

Knaup, F. H.; Meyners, C.; Sugiarto, W. O.; Wedel, S.; Springer, M.; Walz, C.; Geiger, T. M.; Schmidt, M.; Sisignano, M.; Hausch, F.: Statistical Models for Predicting Oil Composition from Hydrothermal Liquefaction of Biomass. JOURNAL OF MEDICINAL CHEMISTRY 66 (8), pp. 5965 - 5980 (2023)

Kos, A.; Lopez, J. P.; Bordes, J.; De Donno, C.; Dine, J.; Brivio, E.; Karamihalev, S.; Luecken, M. D.; de Almeida-Correa, S.; Gasperoni, S. et al.; Dick, A.; Miranda, L.; Buettner, M.; Stoffel, R.; Flachskamm, C.; Theis, F. J.; Schmidt, M. V.; Chen, A.: Early life adversity shapes social subordination and cell type-specific transcriptomic patterning in the ventral hippocampus. SCIENCE ADVANCES 9 (48), eadj3793 (2023)

van Doeselaar, L.; Stark, T.; Mitra, S.; Yang, H.; Bordes, J.; Stolwijk, L.; Engelhardt, C.; Kovarova, V.; Narayan, S.; Brix, L. M. et al.; Springer, M.; Deussing, J. M.; Lopez, J. P.; Czisch, M.; Schmidt, M. V.: Sex-specific and opposed effects of FKBP51 in glutamatergic and GABAergic neurons: Implications for stress susceptibility and resilience. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 (23), e2300722120 (2023)

Wedel, S.; Hahnefeld, L.; Schreiber, Y.; Namendorf, C.; Heymann, T.; Uhr, M.; Schmidt, M. V.; de Bruin, N.; Hausch, F.; Thomas, D. et al.; Geisslinger, G.; Sisignano, M.: SAFit2 ameliorates paclitaxel-induced neuropathic pain by reducing spinal gliosis and elevating pro-resolving lipid mediators. JOURNAL OF NEUROINFLAMMATION 20 (1), 149 (2023)

Yusupov, N.; van Doeselaar, L.; Roeh, S.; Wiechmann, T.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Schmidt, M. V.; Binder, E. B.: Extensive evaluation of DNA methylation of functional elements in the murine Fkbp5 locus using high-accuracy DNA methylation measurement via targeted bisulfite sequencing. EUROPEAN JOURNAL OF NEUROSCIENCE (2023)

Budzinski, M. L.; Sokn, C.; Gobbini, R.; Ugo, B.; Antunica-Noguerol, M.; Senin, S.; Bajaj, T.; Gassen, N. C.; Rein, T.; Schmidt, M. V. et al.; Binder, E. B.; Arzt, E.; Liberman, A. C.: Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity. MOLECULAR PSYCHIATRY (2022)

Brix, L. M.; Haeusl, A. S.; Toksoez, I.; Bordes, J.; van Doeselaar, L.; Engelhardt, C.; Narayan, S.; Springer, M.; Sterlemann, V.; Deussing, J. M. et al.; Chen, A.; Schmidt, M. V.: The co-chaperone FKBP51 modulates HPA axis activity and age-related maladaptation of the stress system in pituitary proopiomelanocortin cells. PSYCHONEUROENDOCRINOLOGY 138, 105670 (2022)

Brix, L.; Toksöz, I.; Aman, L.; Kovarova, V.; Springer, M.; Bordes, J.; van Doeselaar, L.; Engelhardt, C.; Haeusl, A. S.; Narayan, S. et al.; Sterlemann, V.; Yang, H.; Deussing, J. M.; Schmidt, M. V.: Contribution of the co-chaperone FKBP51 in the ventromedial hypothalamus to metabolic homeostasis in male and female mice. MOLECULAR METABOLISM 65, 101579 (2022)

Gerstner, N.; Krontira, A. C.; Cruceanu, C.; Roeh, S.; Puetz, B.; Sauer, S.; Rex-Haffner, M.; Schmidt, M. V.; Binder, E. B.; Knauer-Arloth, J.: DiffBrainNet: Differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regions. NEUROBIOLOGY OF STRESS 21, 100496 (2022)