Publications of Torsten Klengel

Joehanes, R.; Just, A. C.; Marioni, R. E.; Pilling, L. C.; Reynolds, L. M.; Mandaviya, P. R.; Guan, W.; Xu, T.; Elks, C. E.; Aslibekyan, S. et al.; Moreno-Macias, H.; Smith, J. A.; Brody, J. A.; Dhingra, R.; Yousefi, P.; Pankow, J. S.; Kunze, S.; Shah, S. H.; McRae, A. F.; Lohman, K.; Sha, J.; Absher, D. M.; Ferrucci, L.; Zhao, W.; Demerath, E. W.; Bressler, J.; Grove, M. L.; Huan, T.; Liu, C.; Mendelson, M. M.; Yao, C.; Kiel, D. P.; Peters, A.; Wang-Sattler, R.; Visscher, P. M.; Wray, N. R.; Starr, J. M.; Ding, J.; Rodriguez, C. J.; Wareham, N. J.; Irvin, M. R.; Zhi, D.; Barrdahl, M.; Vineis, P.; Ambatipudi, S.; Uitterlinden, A. G.; Hofman, A.; Schwartz, J.; Colicino, E.; Hou, L.; Vokonas, P. S.; Hernandez, D. G.; Singleton, A. B.; Bandinelli, S.; Turner, S. T.; Ware, E. B.; Smith, A. K.; Klengel, T.; Binder, E. B.; Psaty, B. M.; Taylor, K. D.; Gharib, S. A.; Swenson, B. R.; Liang, L.; DeMeo, D. L.; O'Connor, G. T.; Herceg, Z.; Ressler, K. J.; Conneely, K. N.; Sotoodehnia, N.; Kardia, S. L. R.; Melzer, D.; Baccarelli, A. A.; van Meurs, J. B. J.; Romieu, I.; Arnett, D. K.; Ong, K. K.; Liu, Y.; Waldenberger, M.; Deary, I. J.; Fornage, M.; Levy, D.; London, S. J.: Epigenetic Signatures of Cigarette Smoking. CIRCULATION-CARDIOVASCULAR GENETICS 9 (5), pp. 436 - 447 (2016)

Yehuda, R.; Daskalakis, N. P.; Bierer, L. M.; Bader, H. N.; Klengel, T.; Holsboer, F.; Binder, E. B.: Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation. BIOLOGICAL PSYCHIATRY 80 (5), pp. 372 - 380 (2016)

Peters, M. J.; Joehanes, R.; Pilling, L. C.; Schurmann, C.; Conneely, K. N.; Powell, J.; Reinmaa, E.; Sutphin, G. L.; Zhernakova, A.; Schramm, K. et al.; Wilson, Y. A.; Kobes, S.; Tukiainen, T.; Ramos, Y. F.; Goering, H. H. H.; Fornage, M.; Liu, Y.; Gharib, S. A.; Stranger, B. E.; De Jager, P. L.; Aviv, A.; Levy, D.; Murabito, J. M.; Munson, P. J.; Huan, T.; Hofman, A.; Uitterlinden, A. G.; Rivadeneira, F.; van Rooij, J.; Stolk, L.; Broer, L.; Verbiest, M. M. P. J.; Jhamai, M.; Arp, P.; Metspalu, A.; Tserel, L.; Milani, L.; Samani, N. J.; Peterson, P.; Kasela, S.; Codd, V.; Peters, A.; Ward-Caviness, C. K.; Herder, C.; Waldenberger, M.; Roden, M.; Singmann, P.; Zeilinger, S.; Illig, T.; Homuth, G.; Grabe, H.-J.; Voelzke, H.; Steil, L.; Kocher, T.; Murray, A.; Melzer, D.; Yaghootkar, H.; Bandinelli, S.; Moses, E. K.; Kent, J. W.; Curran, J. E.; Johnson, M. P.; Williams-Blangero, S.; Westra, H.-J.; Mcrae, A. F.; Smith, J. A.; Kardia, S. L. R.; Hovatta, I.; Perola, M.; Ripatti, S.; Salomaa, V.; Henders, A. K.; Martin, N. G.; Smith, A. K.; Mehta, D.; Binder, E. B.; Nylocks, K. M.; Kennedy, E. M.; Klengel, T.; Ding, J.; Suchy-Dicey, A. M.; Enquobahrie, D. A.; Brody, J.; Rotter, J. I.; Chen, Y.-D. I.; Houwing-Duistermaat, J.; Kloppenburg, M.; Slagboom, P. E.; Helmer, Q.; den Hollander, W.; Bean, S.; Raj, T.; Bakhshi, N.; Wang, Q. P.; Oyston, L. J.; Psaty, B. M.; Tracy, R. P.; Montgomery, G. W.; Turner, S. T.; Blangero, J.; Meulenbelt, I.; Ressler, K. J.; Yang, J.; Franke, L.; Kettunen, J.; Visscher, P. M.; Neely, G. G.; Korstanje, R.; Hanson, R. L.; Prokisch, H.; Ferrucci, L.; Esko, T.; Teumer, A.; van Meurs, J. B. J.; Johnson, A. D.: The transcriptional landscape of age in human peripheral blood. NATURE COMMUNICATIONS 6, 8570 (2015)

Arloth, J.; Bogdan, R.; Weber, P.; Frishman, G.; Menke, A.; Wagner, K. V.; Balsevich, G.; Schmidt, M. V.; Karbalai, N.; Czamara, D. et al.; Altmann, A.; Truembach, D.; Wurst, W.; Mehta, D.; Uhr, M.; Klengel, T.; Erhardt, A.; Carey, C. E.; Conley, E. D.; Ruepp, A.; Müller-Myhsok, B.; Hariri, A. R.; Binder, E. B.: Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. NEURON 86 (5), pp. 1189 - 1202 (2015)

Klengel, T.; Binder, E. B.: Epigenetics of Stress-Related Psychiatric Disorders and Gene * Environment Interactions. Neuron 86 (6), pp. 1343 - 57 (2015)

Hennings, J. M.; Uhr, M.; Klengel, T.; Weber, P.; Pütz, B.; Touma, C.; Czamara, D.; Ising, M.; Holsboer, F.; Lucae, S.: RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response. Translational psychiatry 5, e538 (2015)

Klengel, T.; Binder, E. B.: FKBP5 Allele-Specific Epigenetic Modification in Gene by Environment Interaction. NEUROPSYCHOPHARMACOLOGY 40 (1), pp. 244 - 246 (2015)

Smith, A. K.; Kilaru, V.; Klengel, T.; Mercer, K. B.; Bradley, B.; Conneely, K. N.; Ressler, K. J.; Binder, E. B.: DNA Extracted From Saliva for Methylation Studies of Psychiatric Traits: Evidence for Tissue Specificity and Relatedness to Brain. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 168 (1), pp. 36 - 44 (2015)

Sabbagh, J. J.; O'Leary III, J. C.; Blair, L. J.; Klengel, T.; Nordhues, B. A.; Fontaine, S. N.; Binder, E. B.; Dickey, C. A.: Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency. PLOS ONE 9 (9), e107241 (2014)

Klengel, T.; Pape, J.; Binder, E. B.; Mehta, D.: The role of DNA methylation in stress-related psychiatric disorders. NEUROPHARMACOLOGY 80, pp. 115 - 132 (2014)

Barfield, R. T.; Almli, L. M.; Kilaru, V.; Smith, A. K.; Mercer, K. B.; Duncan, R.; Klengel, T.; Mehta, D.; Binder, E. B.; Epstein, M. P. et al.; Ressler, K. J.; Conneely, K. N.: Accounting for Population Stratification in DNA Methylation Studies. GENETIC EPIDEMIOLOGY 38 (3), pp. 231 - 241 (2014)

Blair, L. J.; Nordhues, B. A.; Hil, S. E.; Scaglione, M.; O'Leary III, J. C.; Fontaine, S. N.; Breydo, L.; Zhang, B.; Li, P.; Wang, L. et al.; Cotman, C.; Paulson, H. L.; Muscho, M.; Uversky, V. N.; Klengel, T.; Binder, E. B.; Kayed, R.; Golde, T. E.; Berchtold, N.; Dickey, C. A.: Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. JOURNAL OF CLINICAL INVESTIGATION 123 (10), pp. 4158 - 4169 (2013)

Sun, Y. V.; Smith, A. K.; Conneely, K. N.; Chang, Q.; Li, W.; Lazarus, A.; Smith, J. A.; Almli, L. M.; Binder, E. B.; Klengel, T. et al.; Cross, D.; Turner, S. T.; Ressler, K. J.; Kardia, S. L. R.: Epigenomic association analysis identifies smoking-related DNA methylation sites in African Americans. HUMAN GENETICS 132 (9), pp. 1027 - 1037 (2013)

Kloiber, S.; Ripke, S.; Kohli, M. A.; Reppermund, S.; Salyakina, D.; Uher, R.; McGuffin, P.; Perlis, R. H.; Hamilton, S. P.; Puetz, B. et al.; Hennings, J.; Brueckl, T.; Klengel, T.; Bettecken, T.; Ising, M.; Uhr, M.; Dose, T.; Unschuld, P. G.; Zihl, J.; Binder, E.; Mueller-Myhsok, B.; Holsboer, F.; Lucae, S.: Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels. EUROPEAN NEUROPSYCHOPHARMACOLOGY 23 (7), pp. 653 - 662 (2013)

Hennings, J. M.; Kohli, M. A.; Czamara, D.; Giese, M.; Eckert, A.; Wolf, C.; Heck, A.; Domschke, K.; Arolt, V.; Baune, B. T. et al.; Horstmann, S.; Brueckl, T.; Klengel, T.; Menke, A.; Mueller-Myhsok, B.; Ising, M.; Uhr, M.; Lucae, S.: Possible Associations of NTRK2 Polymorphisms with Antidepressant Treatment Outcome: Findings from an Extended Tag SNP Approach. PLOS ONE 8 (6), e64947 (2013)

Mehta, D.; Klengel, T.; Conneely, K. N.; Smith, A. K.; Altmann, A.; Pace, T. W.; Rex-Haffner, M.; Loeschner, A.; Gonik, M.; Mercer, K. B. et al.; Bradley, B.; Mueller-Myhsok, B.; Ressler, K. J.; Binder, E. B.: Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110 (20), pp. 8302 - 8307 (2013)

Norrholm, S. D.; Jovanovic, T.; Smith, A. K.; Binder, E.; Klengel, T.; Conneely, K.; Mercer, K. B.; Davis, J. S.; Kerley, K.; Winkler, J. et al.; Gillespie, C. F.; Bradley, B.; Ressler, K. J.: Differential genetic and epigenetic regulation of catechol-O-methyltransferase is associated with impaired fear inhibition in posttraumatic stress disorder. FRONTIERS IN BEHAVIORAL NEUROSCIENCE 7, 30 (2013)

Klengel, T.; Binder, E. B.: Gene x environment interactions in the prediction of response to antidepressant treatment. International Journal of Neuropsychopharmacology 16 (3), pp. 701 - 711 (2013)

Klengel, T.; Binder, E. B.: Allele-specific epigenetic modification: a molecular mechanism for gene-environment interactions in stress-related psychiatric disorders? [Editorial]. EPIGENOMICS 5 (2), pp. 109 - 112 (2013)

Klengel, T.; Binder, E. B.: Gene-Environment Interactions in Major Depressive Disorder. CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE 58 (2), pp. 76 - 83 (2013)