Publications of Florian Holsboer

Hartmann, J.; Wagner, K. V.; Gaali, S.; Kirschner, A.; Kozany, C.; Ruhter, G.; Dedic, N.; Häusl, A. S.; Hoeijmakers, L.; Westerholz, S. et al.; Namendorf, C.; Gerlach, T.; Uhr, M.; Chen, A.; Deussing, J. M.; Holsboer, F.; Hausch, F.; Schmidt, M. V.: Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties. The Journal of neuroscience: the official journal of the Society for Neuroscience 35 (24), pp. 9007 - 16 (2015)

Kloiber, S.; Domschke, K.; Ising, M.; Arolt, V.; Baune, B. T.; Holsboer, F.; Lucae, S.: Clinical risk factors for weight gain during psychopharmacologic treatment of depression: results from 2 large German observational studies. The Journal of clinical psychiatry 76 (6), pp. e802 - e808 (2015)

Probst-Schendzielorz, K.; Scholl, C.; Efimkina, O.; Ersfeld, E.; Viviani, R.; Serretti, A.; Fabbri, C.; Gurwitz, D.; Lucae, S.; Ising, M. et al.; Paul, A. M.; Lehmann, M.-L.; Steffens, M.; Crisafulli, C.; Calabro, M.; Holsboer, F.; Stingl, J.: CHL1, ITGB3 and SLC6A4 gene expression and antidepressant drug response: results from the Munich Antidepressant Response Signature (MARS) study. PHARMACOGENOMICS 16 (7), pp. 689 - 701 (2015)

Schmidt, U.; Willmund, G.-D.; Holsboer, F.; Wotjak, C. T.; Gallinat, J.; Kowalski, J. T.; Zimmermann, P.: Searching for non-genetic molecular and imaging PTSD risk and resilience markers: Systematic review of literature and design of the German Armed Forces PTSD biomarker study. PSYCHONEUROENDOCRINOLOGY 51, pp. 444 - 458 (2015)

Höhne, N.; Poidinger, M.; Merz, F.; Pfister, H.; Brückl, T.; Zimmermann, P.; Uhr, M.; Holsboer, F.; Ising, M.: Increased HPA axis response to psychosocial stress in remitted depression: the influence of coping style. BIOLOGICAL PSYCHOLOGY 103, pp. 267 - 275 (2014)

Cuboni, S.; Devigny, C.; Hoogeland, B.; Strasser, A.; Pomplun, S.; Hauger, B.; Hoefner, G.; Wanner, K. T.; Eder, M.; Buschauer, A. et al.; Holsboer, F.; Hausch, F.: Loratadine and Analogues: Discovery and Preliminary Structure-Activity Relationship of Inhibitors of the Amino Acid Transporter B(0)AT2. JOURNAL OF MEDICINAL CHEMISTRY 57 (22), pp. 9473 - 9479 (2014)

Gassen, N. C.; Hartmann, J.; Zschocke, J.; Stepan, J.; Hafner, K.; Zellner, A.; Kirmeier, T.; Kollmannsberger, L.; Wagner, K. V.; Dedic, N. et al.; Balsevich, G.; Deussing, J. M.; Kloiber, S.; Lucae, S.; Holsboer, F.; Eder, M.; Uhr, M.; Ising, M.; Schmidt, M. V.; Rein, T.: Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans. PLOS MEDICINE 11 (11), e1001755 (2014)

Heinzmann, J.-M.; Kloiber, S.; Ebling-Mattos, G.; Bielohuby, M.; Schmidt, M. V.; Palme, R.; Holsboer, F.; Uhr, M.; Ising, M.; Touma, C.: Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: A translational approach. PSYCHONEUROENDOCRINOLOGY 49, pp. 229 - 243 (2014)

Martins-de-Souza, D.; Maccarrone, G.; Ising, M.; Kloiber, S.; Lucae, S.; Holsboer, F.; Turck, C. W.: Blood Mononuclear Cell Proteome Suggests Integrin and Ras Signaling as Critical Pathways for Antidepressant Treatment Response. BIOLOGICAL PSYCHIATRY 76 (7), pp. E15 - E17 (2014)

Seemueller, F.; Meier, S.; Obermeier, M.; Musil, R.; Bauer, M.; Adli, M.; Kronmueller, K.; Holsboer, F.; Brieger, P.; Laux, G. et al.; Bender, W.; Heuser, I.; Zeiler, J.; Gaebel, W.; Riedel, M.; Falkai, P.; Moeller, H.-J.: Three-Year long-term outcome of 458 naturalistically treated inpatients with major depressive episode: severe relapse rates and risk factors. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE 264 (7), pp. 567 - 575 (2014)

Kuempfel, T.; Schwan, M.; Weber, F.; Holsboer, F.; Trenkwalder, C.; Bergh, F. T.: Hypothalamo-pituitary-adrenal axis activity evolves differentially in untreated versus treated multiple sclerosis. PSYCHONEUROENDOCRINOLOGY 45, pp. 87 - 95 (2014)

Labermaier, C.; Kohl, C.; Hartmann, J.; Devigny, C.; Altmann, A.; Weber, P.; Arloth, J.; Quast, C.; Wagner, K. V.; Scharf, S. H. et al.; Czibere, L.; Widner-Andrä, R.; Brenndörfer, J.; Landgraf, R.; Hausch, F.; Jones, K. A.; Mueller, M. B.; Uhr, M.; Holsboer, F.; Binder, E. B.; Schmidt, M. V.: A Polymorphism in the Crhr1 Gene Determines Stress Vulnerability in Male Mice. ENDOCRINOLOGY 155 (7), pp. 2500 - 2510 (2014)

Menke, A.; Arloth, J.; Gerber, M.; Rex-Haffner, M.; Uhr, M.; Holsboer, F.; Binder, E. B.; Holsboer-Trachsler, E.; Beck, J.: Dexamethasone stimulated gene expression in peripheral blood indicates glucocorticoid-receptor hypersensitivity in job-related exhaustion. PSYCHONEUROENDOCRINOLOGY 44, pp. 35 - 46 (2014)

Santarelli, S.; Lesuis, S. L.; Wang, X.-D.; Wagner, K. V.; Hartmann, J.; Labermaier, C.; Scharf, S. H.; Müller, M. B.; Holsboer, F.; Schmidt, M. V.: Evidence supporting the match/mismatch hypothesis of psychiatric disorders. EUROPEAN NEUROPSYCHOPHARMACOLOGY 24 (6), pp. 907 - 918 (2014)

Breitenstein, B.; Scheuer, S.; Holsboer, F.: Are there meaningful biomarkers of treatment response for depression? DRUG DISCOVERY TODAY 19 (5), pp. 539 - 561 (2014)

Albu, S.; Romanowski, C. P. N.; Curzi, M. L.; Jakubcakova, V.; Flachskamm, C.; Gassen, N. C.; Hartmann, J.; Schmidt, M. V.; Schmidt, U.; Rein, T. et al.; Holsboer, F.; Hausch, F.; Paez-Pareda, M.; Kimura, M.: Deficiency of FK506-binding protein ( FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice. JOURNAL OF SLEEP RESEARCH 23 (2), pp. 176 - 185 (2014)

Breitenstein, B.; Scheuer, S.; Pfister, H.; Uhr, M.; Lucae, S.; Holsboer, F.; Ising, M.; Brückl, T. M.: The clinical application of ABCB1 genotyping in antidepressant treatment: a pilot study. CNS SPECTRUMS 19 (2), pp. 165 - 175 (2014)

Dresler, M.; Spoormaker, V. I.; Beitinger, P.; Czisch, M.; Kimura, M.; Steiger, A.; Holsboer, F.: Neuroscience-driven discovery and development of sleep therapeutics. PHARMACOLOGY & THERAPEUTICS 141 (3), pp. 300 - 334 (2014)

Sotnikov, S. V.; Markt, P. O.; Malik, V.; Chekmareva, N. Y.; Naik, R. R.; Sah, A.; Singewald, N.; Holsboer, F.; Czibere, L.; Landgraf, R.: Bidirectional rescue of extreme genetic predispositions to anxiety: impact of CRH receptor 1 as epigenetic plasticity gene in the amygdala. TRANSLATIONAL PSYCHIATRY 4, e359 (2014)

Holsboer, F.: Redesigning antidepressant drug discovery. [Guest Editorial]. Dialogues in clinical neuroscience 16 (1), pp. 5 - 7 (2014)