Publications of J. Zschocke

Gassen, N. C.; Hartmann, J.; Zannas, A. S.; Kretzschmar, A.; Zschocke, J.; Maccarrone, G.; Hafner, K.; Zellner, A.; Kollmannsberger, L. K.; Wag, K. V. et al.; Mehta, D.; Kloiber, S.; Turck, C. W.; Lucae, S.; Chrousos, G. P.; Holsboer, F.; Binder, E. B.; Ising, M.; Schmidt, M. V.; Rein, T.: FKBP51 inhibits GSK3 beta and augments the effects of distinct psychotropic medications. MOLECULAR PSYCHIATRY 21 (2), pp. 277 - 289 (2016)

Gassen, N. C.; Fries, G. R.; Zannas, A. S.; Hartmann, J.; Zschocke, J.; Hafner, K.; Carrillo-Roa, T.; Steinbacher, J.; Preißinger, S. N.; Hoeijmakers, L. et al.; Knop, M.; Weber, F.; Kloiber, S.; Lucae, S.; Chrousos, G. P.; Carell, T.; Ising, M.; Binder, E. B.; Schmidt, M. V.; Ruegg, J.; Rein, T.: Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine. Science signaling 8 (404), p. ra119 - ra119 (2015)

Gassen, N. C.; Hartmann, J.; Zschocke, J.; Stepan, J.; Hafner, K.; Zellner, A.; Kirmeier, T.; Kollmannsberger, L.; Wagner, K. V.; Dedic, N. et al.; Balsevich, G.; Deussing, J. M.; Kloiber, S.; Lucae, S.; Holsboer, F.; Eder, M.; Uhr, M.; Ising, M.; Schmidt, M. V.; Rein, T.: Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans. PLOS MEDICINE 11 (11), e1001755 (2014)

Knapp, R. T.; Wong, M. J. H.; Kollmannsberger, L. K.; Gassen, N. C.; Kretzschmar, A.; Zschocke, J.; Hafner, K.; Young, J. C.; Rein, T.: Hsp70 Cochaperones HspBP1 and BAG-1M Differentially Regulate Steroid Hormone Receptor Function. PLOS ONE 9 (1), e85415 (2014)

Zschocke, J.; Weber, P.; Zimmermann, N.; Rein, T.: Comparison of Glucocorticoid Receptor- and Epigenetically Regulated Genes in Proliferating Versus Growth-Arrested Neuro-2a Cells. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS 12 (8), pp. 1194 - 1204 (2013)

Zimmermann, N.; Zschocke, J.; Perisic, T.; Yu, S.; Holsboer, F.; Rein, T.: Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels. Biochemical Journal 448, pp. 93 - 102 (2012)

Perisic, T.; Holsboer, F.; Rein, T.; Zschocke, J.: The CpG island shore of the GLT-1 gene acts as a methylation-sensitive enhancer. GLIA 60 (9), pp. 1345 - 1355 (2012)

Zschocke, J.; Rein, T.: Antidepressants encounter autophagy in neural cells. Autophagy 7 (10), pp. 1247 - 1248 (2011)

Perisic, T.; Zschocke, J.; Rein, T.: A possible role of repressive chromatin marks in GLT-1 unresponsivity to dexamethasone in rat cerebellar astrocytes. Pharmacopsychiatry 44 (6), p. 303 - 303 (2011)

Zimmermann, N.; Zschocke, J.; Perisic, T.; Yu, S.; Almeida, O. F.; Holsboer, F.; Rein, T.: Mechanistic aspects of cell type and drug specific inhibition of DNA methyltransferase 1. Pharmacopsychiatry 44 (6), p. 312 - 312 (2011)

Zschocke, J.; Zimmermann, N.; Berning, B.; Ganal, V.; Holsboer, F.; Rein, T.: Antidepressant Drugs Diversely Affect Autophagy Pathways in Astrocytes and Neurons-Dissociation from Cholesterol Homeostasis. Neuropsychopharmacology 36 (8), pp. 1754 - 1768 (2011)

Zimmermann, N.; Perisic, T.; Hafner, K.; Uhr, M.; Holsboer, F.; Zschocke, J.; Rein, T.: The epigenetic machinery of neural cells is modulated by psychoactive drugs. European Neuropsychopharmacology 21 (Suppl. 1), pp. S21 - S22 (2011)

Perisic, T.; Zimmermann, N.; Kirmeier, T.; Asmus, M.; Tuorto, F.; Uhr, M.; Holsboer, F.; Rein, T.; Zschocke, J.: Valproate and Amitriptyline Exert Common and Divergent Influences on Global and Gene Promoter-Specific Chromatin Modifications in Rat Primary Astrocytes. Neuropsychopharmacology 35 (3), pp. 792 - 805 (2010)

Perisic, T.; Rein, T.; Zschocke, J.: The epigenetic status of the GLT-1 promoter is influenced by drugs with histone deacetylase inhibitor properties. Pharmacopsychiatry 42 (5), pp. 235 - 236 (2009)

Zimmermann, N.; Zschocke, J.; Bettecken, T.; Pütz, B.; Holsboer, F.; Rein, T.: Characterisation of DNA methylation marks in stress exposed hippocampal astrocytes. Pharmacopsychiatry 42 (5), p. 249 - 249 (2009)

Zschocke, J.; Rein, T.: Profiling of stress-induced epigenetic alterations in neuronal Neuro-2a cells. Pharmacopsychiatry 42 (5), p. 249 - 249 (2009)

Laenger, A.; Lang-Rollin, I.; Kozany, C.; Zschocke, J.; Zimmermann, N.; Ruegg, J.; Holsboer, F.; Hausch, F.; Rein, T.: XAP2 inhibits glucocorticoid receptor activity in mammalian cells. FEBS Letters 583 (9), pp. 1493 - 1498 (2009)

Perisic, T.; Zschocke, J.; Kirmeier, T.; Uhr, M.; Asmus, M.; Rein, T.: Evaluation of epigenetic effects of psychoactive drugs in primary astrocytes. European Neuropsychopharmacology 19 (Suppl. 1), pp. S22 - S23 (2009)

Zschocke, J.; Allritz, C.; Engele, J.; Rein, T.: Epigenetic regulation of the human EAAT2 gene expression in glioma cells and normal brain. Pharmacopsychiatry 40 (5), p. 251 - 251 (2007)

Zschocke, J.; Allritz, C.; Engele, J.; Rein, T.: DNA methylation dependent silencing of the human glutamate transporter EAAT2 gene in glial cells. GLIA 55 (7), pp. 663 - 674 (2007)