Publications Jan Deussing

Evangelos, K.; Gottschalk, M.; Kläffgen, S.; Deussing, J. M.; Erhardt, A.; Pape, J.-C.; von Mücke-Heim, I.-A.: Contemporary in vivo rodent electroconvulsive therapy (ECT) models in translational depression research: a systematic review. Translational psychiatry 15 (1), 515 (2025)

Zhang, J.; Gu, J.; Li, Y.; Hao, Z.; Zhao, C.; Deussing, J. M.; Li, Y.: Internalized Stigma in Patients With Schizophrenia in Rural China: Prevalence and Associated Factors. INTERNATIONAL JOURNAL OF SOCIAL PSYCHIATRY (2025)

Broccoli, L.; Bernardi, R. E.; Giannone, F.; Hoppe, A.; Jungling, K.; Borroto-Escuela, D. O.; Rimondini-Giorgini, R.; de la Mora, M. P.; von Bohlen Und Halbach, O.; Fuxe, K. et al.; Pape, H.-C.; Deussing, J. M.; Spanagel, R.; Sommer, W. H.; Hansson, A. C.: Reducing stress and alcohol-related behaviors by targeting D1-CRHR1 receptor interactions in the amygdala. FRONTIERS IN PHARMACOLOGY 16, 1677510 (2025)

Kovarova, V.; Bordes, J.; Mitra, S.; Narayan, S.; Springer, M.; Brix, L.; Deussing, J. M.; Schmidt, M. V.: Deep phenotyping reveals CRH and FKBP51-dependent behavioral profiles following chronic social stress exposure in male mice. Neuropsychopharmacology 50 (3), pp. 556 - 567 (2025)

Ries, C.; Stark, T.; Boulat, B.; Ruhwedel, T.; Delling, J.-P.; Infante, A. M.; von Poblotzki, J. T.; Ulivi, A.; von Mücke-Heim, I.-A.; Chang, S. et al.; Sakimura, K.; Itoi, K.; Nestvogel, D.; Attardo, A.; Czisch, M.; Nave, K.-A.; Mobius, W.; Dimou, L.; Deussing, J. M.: Neuropeptide CRH prevents premature differentiation of OPCs following CNS injury and in early postnatal development. Cell reports 44 (11), 116474 (2025)

Sen, P.; Ortiz, O.; Brivio, E.; Menegaz, D.; Sotillos Elliott, L.; Du, Y.; Ries, C.; Chen, A.; Wurst, W.; Lopez, J. P. et al.; Eder, M.; Deussing, J. M.: A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior. Molecular Psychiatry 30 (1), pp. 97 - 110 (2025)

van Doeselaar, L.; Abromeit, A.; Stark, T.; Menegaz, D.; Ballmann, M.; Mitra, S.; Yang, H.; Rehawi, G.; Huettl, R. E.; Bordes, J. et al.; Narayan, S.; Harbich, D.; Deussing, J. M.; Rammes, G.; Czisch, M.; Knauer-Arloth, J.; Eder, M.; Lopez, J. P.; Schmidt, M. V.: FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice. Nature Communications 16 (1), 2529 (2025)

von Mucke-Heim, I.-A.; Oldekamp, J.; Metzger Michael, M. W.; Klaffgen, S.; Tang, H.; Walser, S. M.; Dedic, N.; Rammes, G.; Holsboer, F.; Wurst, W. et al.; Deussing, J. M.: Establishment and behavioural characterization of a novel constitutive P2X7 receptor knockout mouse line. Purinergic signalling 21, pp. 1077 - 1092 (2025)

Cheng, X.-Y.; Ren, W.-J.; Li, X.; Deussing, J. M.; Illes, P.; Tang, Y.; Rubini, P.: Astrocytic P2X7 receptor regulates depressive-like behavioral reactions of mice in response to acute stressful stimulation. PURINERGIC SIGNALLING 21 (4), pp. 687 - 694 (2024)

Giusti, S. A.; Pino, N. S.; Pannunzio, C.; Ogando, M. B.; Armando, N. G.; Garrett, L.; Zimprich, A.; Becker, L.; Gimeno, M. L.; Lukin, J. et al.; Merino, F. L.; Pardi, M. B.; Pedroncini, O.; Di Mauro, G. C.; Durner, V. G.; Fuchs, H.; de Angelis, M. H.; Patop, I. L.; Turck, C. W.; Deussing, J. M.; Weisenhorn, D. M. V.; Jahn, O.; Kadener, S.; Hoelter, S. M.; Brose, N.; Giesert, F.; Wurst, W.; Marin-Burgin, A.; Refojo, D.: A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli. SCIENCE ADVANCES 10 (21), eadj8769 (2024)

Loganathan, S.; Menegaz, D.; Delling, J.-P.; Eder, M.; Deussing, J. M.: Cacna1c deficiency in forebrain glutamatergic neurons alters behavior and hippocampal plasticity in female mice. Translational Psychiatry 14 (1), 421 (2024)

Stepan, J.; Heinz, D. E.; Dethloff, F.; Wiechmann , S.; Martinelli, S.; Hafner, K.; Ebert, T.; Junglas, E.; Haeusl, A. S.; Poehlmann, M. L. et al.; Jakovcevski, M.; Pape, J. C.; Zannas, A. S.; Bajaj , T.; Hermann, A.; Ma, X.; Pavenstaedt, H.; Schmidt, M. V.; Philipsen, A.; Turck, C. W.; Deussing, J. M.; Rammes, G.; Robinson, A. C.; Payton, A.; Wehr, M. C.; Stein, V.; Murgatroyd, C.; Kremerskothen, J.; Kuster, B.; Wotjak, C. T.; Gassen, N. C.: Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice. SCIENCE SIGNALING 17 (834), eadj6603 (2024)

Yusupov, N.; Roeh, S.; Sotillos Elliott, L.; Chang, S.; Loganathan, S.; Urbina Trevino, L.; Fröhlich, A. S.; Sauer, S.; Ködel, M.; Matosin, N. et al.; Czamara, D.; Deussing, J. M.; Binder, E. B.: DNA methylation patterns of FKBP5 regulatory regions in brain and blood of humanized mice and humans. Molecular Psychiatry (2024)

Han, J.; Zhao, C.; Guo, H.; Liu, T.; Li, Y.; Qi, Y.; Deussing, J. M.; Zhang, Y.; Tan, J.; Han, H. et al.; Ma, X.: Obesity induces male mice infertility via oxidative stress, apoptosis, and glycolysis. REPRODUCTION 166 (1), pp. 27 - 36 (2023)

van Doeselaar, L.; Stark, T.; Mitra, S.; Yang, H.; Bordes, J.; Stolwijk, L.; Engelhardt, C.; Kovarova, V.; Narayan, S.; Brix, L. M. et al.; Springer, M.; Deussing, J. M.; Lopez, J. P.; Czisch, M.; Schmidt, M. V.: Sex-specific and opposed effects of FKBP51 in glutamatergic and GABAergic neurons: Implications for stress susceptibility and resilience. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 (23), e2300722120 (2023)

von Mucke-Heim, I.-A.; Deussing, J. M.: The P2X7 receptor in mood disorders: Emerging target in immunopsychiatry, from bench to bedside. NEUROPHARMACOLOGY 224, 109366 (2023)

von Mücke-Heim, I.-A.; Martin, J.; Uhr, M.; Ries, C.; Deussing, J. M.: The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation. Frontiers in Pharmacology 14, 1148190 (2023)

von Muecke-Heim, I.-A.; Pape, J. C.; Grandi, N. C.; Erhardt, A.; Deussing, J. M.; Binder, E. B.: Multiomics and blood-based biomarkers of electroconvulsive therapy in severe and treatment-resistant depression: study protocol of the DetECT study. European Archives of Psychiatry and Clinical Neuroscience (2023)

Zhao, C.; Ries, C.; Du, Y.; Zhang, J.; Sakimura, K.; Itoi, K.; Deussing, J. M.: Differential CRH expression level determines efficiency of Cre- and Flp-dependent recombination. Frontiers in Neuroscience 17, 1163462 (2023)

Brix, L. M.; Haeusl, A. S.; Toksoez, I.; Bordes, J.; van Doeselaar, L.; Engelhardt, C.; Narayan, S.; Springer, M.; Sterlemann, V.; Deussing, J. M. et al.; Chen, A.; Schmidt, M. V.: The co-chaperone FKBP51 modulates HPA axis activity and age-related maladaptation of the stress system in pituitary proopiomelanocortin cells. PSYCHONEUROENDOCRINOLOGY 138, 105670 (2022)