Publications Jan Deussing

Han, J.; Zhao, C.; Guo, H.; Liu, T.; Li, Y.; Qi, Y.; Deussing, J. M.; Zhang, Y.; Tan, J.; Han, H. et al.; Ma, X.: Obesity induces male mice infertility via oxidative stress, apoptosis, and glycolysis. REPRODUCTION 166 (1), pp. 27 - 36 (2023)

van Doeselaar, L.; Stark, T.; Mitra, S.; Yang, H.; Bordes, J.; Stolwijk, L.; Engelhardt, C.; Kovarova, V.; Narayan, S.; Brix, L. M. et al.; Springer, M.; Deussing, J. M.; Lopez, J. P.; Czisch, M.; Schmidt, M. V.: Sex-specific and opposed effects of FKBP51 in glutamatergic and GABAergic neurons: Implications for stress susceptibility and resilience. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 (23), e2300722120 (2023)

von Mucke-Heim, I.-A.; Deussing, J. M.: The P2X7 receptor in mood disorders: Emerging target in immunopsychiatry, from bench to bedside. NEUROPHARMACOLOGY 224, 109366 (2023)

von Mücke-Heim, I.-A.; Martin, J.; Uhr, M.; Ries, C.; Deussing, J. M.: The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation. FRONTIERS IN PHARMACOLOGY 14, 1148190 (2023)

von Muecke-Heim, I.-A.; Pape, J. C.; Grandi, N. C.; Erhardt, A.; Deussing, J. M.; Binder, E. B.: Multiomics and blood-based biomarkers of electroconvulsive therapy in severe and treatment-resistant depression: study protocol of the DetECT study. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2023)

Zhao, C.; Ries, C.; Du, Y.; Zhang, J.; Sakimura, K.; Itoi, K.; Deussing, J. M.: Differential CRH expression level determines efficiency of Cre- and Flp-dependent recombination. FRONTIERS IN NEUROSCIENCE 17, 1163462 (2023)

Brix, L. M.; Haeusl, A. S.; Toksoez, I.; Bordes, J.; van Doeselaar, L.; Engelhardt, C.; Narayan, S.; Springer, M.; Sterlemann, V.; Deussing, J. M. et al.; Chen, A.; Schmidt, M. V.: The co-chaperone FKBP51 modulates HPA axis activity and age-related maladaptation of the stress system in pituitary proopiomelanocortin cells. PSYCHONEUROENDOCRINOLOGY 138, 105670 (2022)

Brix, L.; Toksöz, I.; Aman, L.; Kovarova, V.; Springer, M.; Bordes, J.; van Doeselaar, L.; Engelhardt, C.; Haeusl, A. S.; Narayan, S. et al.; Sterlemann, V.; Yang, H.; Deussing, J. M.; Schmidt, M. V.: Contribution of the co-chaperone FKBP51 in the ventromedial hypothalamus to metabolic homeostasis in male and female mice. MOLECULAR METABOLISM 65, 101579 (2022)

Chang, S.; Fermani, F.; Lao, C.-L.; Huang, L.; Jakovcevski, M.; Di Giaimo, R.; Gagliardi, M.; Menegaz, D.; Hennrich, A. A.; Ziller, M. et al.; Eder, M.; Klein, R.; Cai, N.; Deussing, J. M.: Tripartite extended amygdala-basal ganglia CRH circuit drives locomotor activation and avoidance behavior. SCIENCE ADVANCES 8 (46) (2022)

Lopez, J. P.; Luecken, M. D.; Brivio, E.; Karamihalev, S.; Kos, A.; De Donno, C.; Benjamin, A.; Yang, H.; Dick, A. L. W.; Stoffel, R. et al.; Flachskamm, C.; Ressle, A.; Roeh, S.; Huettl, R. E.; Parl, A.; Eggert, C.; Novak, B.; Yan, Y.; Yeoh, K.; Lebar, M.; Hauger, B.; Harbich, D.; Schmid, B.; Di Giaimo, R.; Turck, C. W.; Schmidt, M. V.; Deussing, J. M.; Eder, M.; Dine, J.; Theis, F. J.; Chen, A.: Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2. NEURON 110 (14), pp. 2283 - 2298.e9 (2022)

Stepan, J.; Heinz, D. E.; Dethloff, F.; Bajaj, T.; Zellner, A.; Hafner, K.; Wiechmann, S.; Mackert, S.; Mecdad, Y.; Rabenstein, M. et al.; Ebert, T.; Martinelli, S.; Haeusl, A. S.; Poehlmann, M. L.; Hermann, A.; Ma, X.; Pavenstaedt, H.; Schmidt, M. V.; Philipsen, A.; Turck, C. W.; Deussing, J. M.; Kuster, B.; Wehr, M. C.; Stein, V.; Kremerskothen, J.; Wotjak, C. T.; Gassen, N. C.: Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning. CELL REPORTS 41 (10), 111766 (2022)

Zalachoras, I.; Astori, S.; Meijer, M.; Grosse, J.; Zanoletti, O.; de Suduiraut, I. G.; Deussing, J. M.; Sandi, C.: Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA. SCIENCE ADVANCES 8 (12), eabj9019 (2022)

Zhao, Y.-F.; Ren, W.-J.; Zhang, Y.; He, J.-R.; Yin, H.-Y.; Liao, Y.; Rubini, P.; Deussing, J. M.; Verkhratsky, A.; Yuan, Z.-Q. et al.; Illes, P.; Tang, Y.: High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (3), 1904 (2022)

Pagella, S.; Deussing, J. M.; Kopp-Scheinpflug, C.: Expression Patterns of the Neuropeptide Urocortin 3 and Its Receptor CRFR2 in the Mouse Central Auditory System. FRONTIERS IN NEURAL CIRCUITS 15, 747472 (2021)

Ruat, J.; Hartmann, A.; Heinz, D. E.; Nemcova, P.; Stoffel, R.; Deussing, J. M.; Chen, A.; Wotjak, C. T.: CB1 receptors in corticotropin-releasing factor neurons selectively control the acoustic startle response in male mice. GENES BRAIN AND BEHAVIOR, e12775 (2021)

Hausl, A. S.; Brix, L.; Hartmann, J.; Poehlmann, M. L.; Lopez, J. P.; Menegaz, D.; Brivio, E.; Engelhardt, C.; Roeh, S.; Bajaj, T. et al.; Rudolph, L.; Stoffel, R.; Hafner, K.; Goss, H. M.; Reul, J. M. H. M.; Deussing, J. M.; Eder, M.; Ressler, K. J.; Gassen, N. C.; Chen, A.; Schmidt, M. V.: The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. MOLECULAR PSYCHIATRY (2021)

Engel, T.; Nicke, A.; Deussing, J. M.; Sperlagh, B.; Diaz-Hernandez, M.: Editorial: P2X7 as Common Therapeutic Target in Brain Diseases. FRONTIERS IN MOLECULAR NEUROSCIENCE 14, 656011 (2021)

Narendran, S.; Pereira, F.; Yerramothu, P.; Apicella, I.; Wang, S.-b.; Ambati, K.; Hirahara, S.; Kim, Y.; Ambati, M.; Ambati, V. L. et al.; Huang, P.; Varshney, A.; Nagasaka, Y.; Fukuda, S.; Baker, K. L.; Marion, K. M.; Deussing, J. M.; Sadda, S. R.; Gelfand, B. D.; Ambati, J.: Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-beta induced retinal pigmented epithelium degeneration. SIGNAL TRANSDUCTION AND TARGETED THERAPY 6 (1), 149 (2021)

Silberstein, S.; Liberman, A. C.; dos Santos Claro, P. A.; Ugo, M. B.; Deussing, J. M.; Arzt, E.: Stress-Related Brain Neuroinflammation Impact in Depression: Role of the Corticotropin-Releasing Hormone System and P2X7 Receptor. NEUROIMMUNOMODULATION 28 (2), pp. 52 - 60 (2021)

von Muecke-Heim, I.-A.; Ries, C.; Urbina, L.; Deussing, J. M.: P2X7R antagonists in chronic stress-based depression models: a review. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE 271 (7), pp. 1343 - 1358 (2021)