Publications of Theo Rein

Fries, G. R.; Gassen, N. C.; Rein, T.: The FKBP51 Glucocorticoid Receptor Co-Chaperone: Regulation, Function, and Implications in Health and Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 18 (12), 2614 (2017)

Vater, M.; Moeckl, L.; Gormanns, V.; Fademrecht, C. S.; Mallmann, A. M.; Ziegart-Sadowska, K.; Zaba, M.; Frevert, M. L.; Braeuchle, C.; Holsboer, F. et al.; Rein, T.; Schmidt, U.; Kirmeier, T.: New insights into the intracellular distribution pattern of cationic amphiphilic drugs. SCIENTIFIC REPORTS 7, 44277 (2017)

Uribe-Marino, A.; Gassen, N. C.; Wiesbeck, M. F.; Balsevich, G.; Santarelli, S.; Solfrank, B.; Dournes, C.; Fries, G. R.; Masana, M.; Labermaier, C. et al.; Wang, X.-D.; Hafner, K.; Schmid, B.; Rein, T.; Chen, A.; Deussing, J. M.; Schmidt, M. V.: Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction. BIOLOGICAL PSYCHIATRY 80 (10), pp. 743 - 753 (2016)

Park, D. I.; Dournes, C.; Sillaber, I.; Uhr, M.; Asara, J. M.; Gassen, N. C.; Rein, T.; Ising, M.; Webhofer, C.; Filiou, M. D. et al.; Müller, M. B.; Turck, C. W.: Purine and pyrimidine metabolism: Convergent evidence on chronic antidepressant treatment response in mice and humans. SCIENTIFIC REPORTS 6, 35317 (2016)

Antunica-Noguerol, M.; Budzinski, M. L.; Druker, J.; Gassen, N. C.; Sokn, M. C.; Senin, S.; Aprile-Garcia, F.; Holsboer, F.; Rein, T.; Liberman, A. C. et al.; Arzt, E.: The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51. CELL DEATH AND DIFFERENTIATION 23 (10), pp. 1579 - 1591 (2016)

Reichel, J. M.; Bedenk, B. T.; Gassen, N. C.; Hafner, K.; Bura, S. A.; Almeida-Correa, S.; Genewsky, A.; Dedic, N.; Giesert, F.; Agarwal, A. et al.; Nave, K. -.; Rein, T.; Czisch, M.; Deussing, J. M.; Wotjak, C. T.: Beware of Your Cre-Ation: lacZ Expression Impairs Neuronal Integrity and Hippocampus-Dependent Memory. HIPPOCAMPUS 26 (10), pp. 1250 - 1264 (2016)

Fries, G. R.; Li, Q.; McAlpin, B.; Rein, T.; Walss-Bass, C.; Soares, J. C.; Quevedo, J.: The role of DNA methylation in the pathophysiology and treatment of bipolar disorder. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 68, pp. 474 - 488 (2016)

Rein, T.: FK506 binding protein 51 integrates pathways of adaptation: FKBP51 shapes the reactivity to environmental change. BIOESSAYS 38 (9), pp. 894 - 902 (2016)

Kirmeier, T.; Gopalakrishnan, R.; Ganal, V.; Werner, A. M.; Cuboni, S.; Rudolf, G. C.; Hoefner, G.; Wanner, K. T.; Sieber, S. A.; Schmidt, U. et al.; Holsboer, F.; Rein, T.; Hausch, F.: Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores. PLOS ONE 11 (2), e0148608 (2016)

Gassen, N. C.; Hartmann, J.; Zannas, A. S.; Kretzschmar, A.; Zschocke, J.; Maccarrone, G.; Hafner, K.; Zellner, A.; Kollmannsberger, L. K.; Wag, K. V. et al.; Mehta, D.; Kloiber, S.; Turck, C. W.; Lucae, S.; Chrousos, G. P.; Holsboer, F.; Binder, E. B.; Ising, M.; Schmidt, M. V.; Rein, T.: FKBP51 inhibits GSK3 beta and augments the effects of distinct psychotropic medications. MOLECULAR PSYCHIATRY 21 (2), pp. 277 - 289 (2016)

Klionsky, D. J.; Gassen, N. C.; Rein, T.; 2511 other, A.: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12 (1), pp. 1 - 222 (2016)

Masana, M.; Jukic, M. M.; Kretzschmar, A.; Wagner, K. V.; Westerholz, S.; Schmidt, M.; Rein, T.; Brodski, C.; Müller, M. B.: DECIPHERING THE SPATIO-TEMPORAL EXPRESSION AND STRESS REGULATION OF FAM107B, THE PARALOG OF THE RESILIENCE-PROMOTING PROTEIN DRR1 IN THE MOUSE BRAIN. NEUROSCIENCE 290, pp. 147 - 158 (2015)

Wagner, K. V.; Hartmann, J.; Labermaier, C.; Häusl, A. S.; Zhao, G.; Harbich, D.; Schmid, B.; Wang, Xiao, X.-D.; Santarelli, S.; Kohl, C. et al.; Gassen, N. C.; Matosin, N.; Schieven, M.; Webhofer, C.; Turck, C. W.; Lindemann, L.; Jaschke, G.; Wettstein, J. G.; Rein, T.; Müller, M. B.; Schmidt, M. V.: Homer1/mGluR5 Activity Moderates Vulnerability to Chronic Social Stress. NEUROPSYCHOPHARMACOLOGY 40 (5), pp. 1222 - 1233 (2015)

Yen, Y.-C.; Gassen, N. C.; Zellner, A.; Rein, T.; Landgraf, R.; Wotjak, C. T.; Anderzhanova, E.: Glycogen synthase kinase-3 beta inhibition in the medial prefrontal cortex mediates paradoxical amphetamine action in a mouse model of ADHD. FRONTIERS IN BEHAVIORAL NEUROSCIENCE 9, 67 (2015)

Gassen, N. C.; Hartmann, J.; Schmidt, M. V.; Rein, T.: FKBP5/FKBP51 enhances autophagy to synergize with antidepressant action. AUTOPHAGY 11 (3), pp. 578 - 580 (2015)

Schmidt, U.; Buell, D. R.; Ionescu, I. A.; Gassen, N. C.; Holsboer, F.; Cox, M. B.; Novak, B.; Huber, C.; Hartmann, J.; Schmidt, M. V. et al.; Touma, C.; Rein, T.; Herrmann, L.: A role for synapsin in FKBP51 modulation of stress responsiveness: Convergent evidence from animal and human studies. PSYCHONEUROENDOCRINOLOGY 52, pp. 43 - 58 (2015)

Gassen, N. C.; Fries, G. R.; Zannas, A. S.; Hartmann, J.; Zschocke, J.; Hafner, K.; Carrillo-Roa, T.; Steinbacher, J.; Preißinger, S. N.; Hoeijmakers, L. et al.; Knop, M.; Weber, F.; Kloiber, S.; Lucae, S.; Chrousos, G. P.; Carell, T.; Ising, M.; Binder, E. B.; Schmidt, M. V.; Ruegg, J.; Rein, T.: Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine. Science signaling 8 (404), p. ra119 - ra119 (2015)

Gassen, N. C.; Hartmann, J.; Zschocke, J.; Stepan, J.; Hafner, K.; Zellner, A.; Kirmeier, T.; Kollmannsberger, L.; Wagner, K. V.; Dedic, N. et al.; Balsevich, G.; Deussing, J. M.; Kloiber, S.; Lucae, S.; Holsboer, F.; Eder, M.; Uhr, M.; Ising, M.; Schmidt, M. V.; Rein, T.: Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans. PLOS MEDICINE 11 (11), e1001755 (2014)

Masana, M.; Su, Y.-A.; Liebl, C.; Wang, X.-D.; Jansen, L.; Westerholz, S.; Wagner, K. V.; Labermaier, C.; Scharf, S. H.; Santarelli, S. et al.; Hartmann, J.; Schmidt, M. V.; Rein, T.; Müller, M. B.: The stress-inducible actin-interacting protein DRR1 shapes social behavior. PSYCHONEUROENDOCRINOLOGY 48, pp. 98 - 110 (2014)

Albu, S.; Romanowski, C. P. N.; Curzi, M. L.; Jakubcakova, V.; Flachskamm, C.; Gassen, N. C.; Hartmann, J.; Schmidt, M. V.; Schmidt, U.; Rein, T. et al.; Holsboer, F.; Hausch, F.; Paez-Pareda, M.; Kimura, M.: Deficiency of FK506-binding protein ( FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice. JOURNAL OF SLEEP RESEARCH 23 (2), pp. 176 - 185 (2014)