Publications Janine Knauer-Arloth

Matosin, N.; Arloth, J.; Czamara, D.; Edmond, K. Z.; Maitra, M.; Froehlich, A. S.; Martinelli, S.; Kaul, D.; Bartlett, R.; Curry, A. R. et al.; Gassen, N. C.; Hafner, K.; Mueller, N. S.; Worf, K.; Rehawi, G.; Nagy, C.; Halldorsdottir, T.; Cruceanu, C.; Gagliardi, M.; Gerstner, N.; Ködel, M.; Murek, V.; Ziller, M. J.; Scarr, E.; Tao, R.; Jaffe, A. E.; Arzberger, T.; Falkai, P.; Kleinmann, J. E.; Weinberger, D. R.; Mechawar, N.; Schmitt, A.; Dean, B.; Turecki, G.; Hyde, T. M.; Binder, E. B.: Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. ACTA NEUROPATHOLOGICA 145 (4), pp. 439 - 459 (2023)

Czamara, D.; Neufang, A.; Dieterle, R.; Iurato, S.; Arloth, J.; Martins, J.; Ising, M.; Binder, E. B.; Erhardt, A.: Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder. CLINICAL EPIGENETICS 14 (1), 55 (2022)

Cruceanu, C.; Dony, L.; Krontira, A. C.; Fischer, D. S.; Roeh, S.; Di Giaimo, R.; Kyrousi, C.; Kaspar, L.; Arloth, J.; Czamara, D. et al.; Gerstner, N.; Martinelli, S.; Wehner, S.; Breen, M. S.; Koedel, M.; Sauer, S.; Sportelli, V.; Rex-Haffner, M.; Cappello, S.; Theis, F. J.; Binder, E. B.: Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study. AMERICAN JOURNAL OF PSYCHIATRY 179 (5), pp. 375 - 387 (2022)

Gerstner, N.; Krontira, A. C.; Cruceanu, C.; Roeh, S.; Puetz, B.; Sauer, S.; Rex-Haffner, M.; Schmidt, M. V.; Binder, E. B.; Knauer-Arloth, J.: DiffBrainNet: Differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regions. NEUROBIOLOGY OF STRESS 21, 100496 (2022)

Kappelmann, N.; Arloth, J.; Georgakis, M. K.; Czamara, D.; Rost, N.; Ligthart, S.; Khandaker, G. M.; Binder, E. B.: Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms A Genetic Correlation and 2-Sample Mendelian Randomization Study. JAMA PSYCHIATRY 78 (2), pp. 161 - 170 (2021)

Kappelmann, N.; Czamara, D.; Rost, N.; Moser, S.; Schmoll, V.; Trastulla, L.; Stochl, J.; Lucae, S.; Binder, E. B.; Khandaker, G. M. et al.; Arloth, J.: Polygenic risk for immuno-metabolic markers and specific depressive symptoms: A multi-sample network analysis study. BRAIN BEHAVIOR AND IMMUNITY 95, pp. 256 - 268 (2021)

Moore, S. R.; Halldorsdottir, T.; Martins, J.; Lucae, S.; Mueller-Myhsok, B.; Mueller, N. S.; Piechaczek, C.; Feldmann, L.; Freisleder, F. J.; Greimel, E. et al.; Schulte-Koerne, G.; Binder, E. B.; Arloth, J.: Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation. TRANSLATIONAL PSYCHIATRY 11 (1), 632 (2021)

Ogris, C.; Hu, Y.; Arloth, J.; Mueller, N. S.: Versatile knowledge guided network inference method for prioritizing key regulatory factors in multi-omics data. SCIENTIFIC REPORTS 11 (1), 6806 (2021)

Arloth, J.; Eraslan, G.; Andlauer, T. F. M.; Martins, J.; Iurato, S.; Kuehnel, B.; Waldenberger, M.; Frank, J.; Gold, R.; Hemmer, B. et al.; Luessi, F.; Nischwitz, S.; Paul, F.; Wiendl, H.; Gieger, C.; Heilmann-Heimbach, S.; Kacprowski, T.; Laudes, M.; Meitinger, T.; Peters, A.; Rawal, R.; Strauch, K.; Lucae, S.; Müller-Myhsok, B.; Rietschel, M.; Theis, F. J.; Binder, E. B.; Mueller, N. S.: DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning. PLOS COMPUTATIONAL BIOLOGY 16 (2), e1007616 (2020)

Provencal, N.; Arloth, J.; Cattaneo, A.; Anacker, C.; Cattane, N.; Wiechmann, T.; Roeh, S.; Koedel, M.; Klengel, T.; Czamara, D. et al.; Mueller, N. S.; Lahti, J.; Raikkonen, K.; Pariante, C. M.; Binder, E. B.: Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (38), pp. 23280 - 23285 (2020)

Elbau, I.; Brucklmeier, B.; Uhr, M.; Arloth, J.; Czamara, D.; Spoormaker, V.; Czisch, M.; Stephan, K. E.; Binder, E. B.; Saemann, P. G.: A polygenic score of molecular sensitivity to GR-stimulation maps to stress related changes of the brains hemodynamic response function. JOURNAL OF NEURAL TRANSMISSION 126 (11), p. 1559 - 1559 (2019)

Elbau, I.; Bruecklmeier, B.; Uhr, M.; Arloth, J.; Czamara, D.; Spoormaker, V.; Czisch, M.; Stephan, K. E.; Binder, E. B.; Saemann, P. G.: A polygenic score of molecular sensitivity to GR-stimulation maps to stress related changes of the brains hemodynamic response function. JOURNAL OF NEURAL TRANSMISSION 126 (11), pp. 1519 - 1520 (2019)

Wiechmann, T.; Roeh, S.; Sauer, S.; Czamara, D.; Arloth, J.; Koedel, M.; Beintner, M.; Knop, L.; Menke, A.; Binder, E. B. et al.; Provencal, N.: Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus. CLINICAL EPIGENETICS 11, 83 (2019)

Zannas, A. S.; Jia, M.; Hafner, K.; Baumert, J.; Wiechmann, T.; Pape, J. C.; Arloth, J.; Koedel, M.; Martinelli, S.; Roitman, M. et al.; Roeh, S.; Haehle, A.; Emeny, R. T.; Iurato, S.; Carrillo-Roa, T.; Lahti, J.; Raikkonen, K.; Eriksson, J. G.; Drake, A. J.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A. K.; Ressler, K. J.; Mueller-Myhsok, B.; Ladwig, K.-H.; Rein, T.; Gassen, N. C.; Binder, E. B.: Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (23), pp. 11370 - 11379 (2019)

Zimmermann, C. A.; Arloth, J.; Santarelli, S.; Loeschner, A.; Weber, P.; Schmidt, M. V.; Spengler, D.; Binder, E. B.: Stress dynamically regulates co-expression networks of glucocorticoid receptor-dependent MDD and SCZ risk genes. TRANSLATIONAL PSYCHIATRY 9, 41 (2019)

Emeny, R. T.; Baumert, J.; Zannas, A. S.; Kunze, S.; Wahl, S.; Iurato, S.; Arloth, J.; Erhardt, A.; Balsevich, G.; Schmidt, M. V. et al.; Weber, P.; Kretschmer, A.; Pfeiffer, L.; Kruse, J.; Strauch, K.; Roden, M.; Herder, C.; Koenig, W.; Gieger, C.; Waldenberger, M.; Peters, A.; Binder, E. B.; Ladwig, K.-H.: Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model. NEUROPSYCHOPHARMACOLOGY 43 (2), pp. 342 - 353 (2018)

Engel, M.; Eggert, C.; Kaplick, P. M.; Eder, M.; Röh, S.; Tietze, L.; Namendorf, C.; Arloth, J.; Weber, P.; Rex-Haffner, M. et al.; Geula, S.; Jakovcevski, M.; Hanna, J. H.; Leshkowitz, D.; Uhr, M.; Wotjak, C. T.; Schmidt, M. V.; Deussing, J. M.; Binder, E. B.; Chen, A.: The Role of m⁶A/m-RNA Methylation in Stress Response Regulation. NEURON 99 (2), pp. 389 - 403 (2018)

Witt, S. H.; Frank, J.; Gilles, M.; Lang, M.; Treutlein, J.; Streit, F.; Wolf, I. A. C.; Peus, V.; Scharnholz, B.; Send, T. S. et al.; Heilmann-Heimbach, S.; Sivalingam, S.; Dukal, H.; Strohmaier, J.; Suetterlin, M.; Arloth, J.; Laucht, M.; Noethen, M. M.; Deuschle, M.; Rietschel, M.: Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation. BMC GENOMICS 19 (1), 290 (2018)

Zannas, A. S.; Arloth, J.; Carrillo-Roa, T.; Iurato, S.; Röh, S.; Ressler, K. J.; Nemeroff, C. B.; Smith, A. K.; Bradley, B.; Heim, C. et al.; Menke, A.; Lange, J. F.; Brückl, T.; Ising, M.; Wray, N. R.; Erhardt, A.; Binder, E. B.; Mehta, D.: Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling (vol 16, 266, 2015). GENOME BIOLOGY 19, 61 (2018)

Iurato, S.; Carrillo-Roa, T.; Arloth, J.; Czamara, D.; Diener-Hölzl, L.; Lange, J.; Müller-Myhsok, B.; Binder, E. B.; Erhardt, A.: DNA Methylation signatures in panic disorder. TRANSLATIONAL PSYCHIATRY 7, 1287 (2017)