Publications of Susann Sauer

Castro-Quintas, A.; Palma-Gudiel, H.; Eixarch, E.; Gonzalez, N. S. M.; Roeh, S.; Sauer, S.; Rex-Haffner, M.; Monteserin-Garcia, J. L.; de la Fuente-tomas, L.; Crispi, F. et al.; Portilla, M. P. G.; Binder, E. B.; Fananas, L.: Placental epigenetic signatures of maternal distress in glucocorticoid-related genes and newborn outcomes: A study of Spanish primiparous women. EUROPEAN NEUROPSYCHOPHARMACOLOGY 90, pp. 36 - 47 (2025)

Hagenberg, J.; Brueckl, T. M.; Erhart, M.; Kopf-Beck, J.; Koedel, M.; Rehawi, G.; Roeh-Karamihalev, S.; Sauer, S.; Yusupov, N.; Rex-Haffner, M. et al.; Spoormaker, V. I.; Saemann, P. G.; Binder, E. B.; Knauer-Arloth, J.: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation. BRAIN BEHAVIOR AND IMMUNITY 123, pp. 353 - 369 (2025)

Vater, M.; Rost, N.; Eckstein, G.; Sauer, S.; Tontsch, A.; Erhardt, A.; Lucae, S.; Brueckl, T.; Klopstock, T.; Sämann, P. G. et al.; Binder, E. B.: Huntingtin CAG repeat size variations below the Huntington's disease threshold: associations with depression, anxiety and basal ganglia structure. EUROPEAN JOURNAL OF HUMAN GENETICS 33 (5), pp. 624 - 632 (2025)

Froehlich, A. S.; Gerstner, N.; Gagliardi, M.; Ködel, M.; Yusupov, N.; Matosin, N.; Czamara, D.; Sauer, S.; Roeh, S.; Murek, V. et al.; Chatzinakos, C.; Daskalakis, N. P.; Knauer-Arloth, J.; Ziller, M. J.; Binder, E. B.: Single-nucleus transcriptomic profiling of human orbitofrontal cortex reveals convergent effects of aging and psychiatric disease. NATURE NEUROSCIENCE 27, pp. 2021 - 2032 (2024)

Grossmann, N. L.; Weihs, A.; Kuehn, L.; Sauer, S.; Roeh, S.; Wiechmann, T.; Rex-Haffner, M.; Voelzke, H.; Voelker, U.; Binder, E. B. et al.; Teumer, A.; Homuth, G.; Klinger-Koenig, J.; Grabe, H. J.: Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 25 (3), 1485 (2024)

Karlbauer, V. N.; Martins, J.; Rex-Haffner, M.; Sauer, S.; Roeh, S.; Dittrich, K.; Doerr, P.; Klawitter, H.; Entringer, S.; Buss, C. et al.; Winter, S. M.; Heim, C.; Czamara, D.; Binder, E. B.: Prenatal exposures and cell type proportions are main drivers of FKBP5 DNA methylation in maltreated and non-maltreated children. NEUROBIOLOGY OF STRESS 33, 100687 (2024)

Krontira, A. C.; Cruceanu, C.; Dony, L.; Kyrousi, C.; Link, M.-H.; Rek, N.; Pöhlchen, D.; Raimundo, C.; Penner-Goeke, S.; Schowe, A. et al.; Czamara, D.; Lahti-Pulkkinen, M.; Sammallahti, S.; Wolford, E.; Heinonen, K.; Roeh, S.; Sportelli, V.; Woelfel, B.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Raikkonen, K.; Labeur, M.; Cappello, S.; Binder, E. B.: Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression. NEURON 112 (9), pp. 1426 - 1443.e11 (2024)

Yusupov, N.; Roeh, S.; Sotillos Elliott, L.; Chang, S.; Loganathan, S.; Urbina Trevino, L.; Fröhlich, A. S.; Sauer, S.; Ködel, M.; Matosin, N. et al.; Czamara, D.; Deussing, J. M.; Binder, E. B.: DNA methylation patterns of FKBP5 regulatory regions in brain and blood of humanized mice and humans. MOLECULAR PSYCHIATRY (2024)

Penner-Goeke, S.; Bothe, M.; Rek, N.; Kreitmaier, P.; Poehlchen, D.; Kühnel, A.; Glaser, L. V.; Kaya, E.; Krontira, A.; Roeh, S. et al.; Czamara, D.; Ködel, M.; Monteserin-Garcia, J.; Diener, L.; Woelfel, B.; Sauer, S.; Rummel, C.; Riesenberg, S.; Arloth-Knauer, J.; Ziller, M.; Labeur, M.; Meijsing, S.; Binder, E. B.: High- throughput screening of glucocorticoid- induced enhancer activity reveals mechanisms of stress- related psychiatric disorders. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 (49), e2305773120 (2023)

Yusupov, N.; Dieckmann, L.; Erhart, M.; Sauer, S.; Rex-Haffner, M.; Kopf-Beck, J.; Brueckl, T. M.; Czamara, D.; Binder, E. B.: Transdiagnostic evaluation of epigenetic age acceleration and burden of psychiatric disorders. NEUROPSYCHOPHARMACOLOGY (2023)

Yusupov, N.; van Doeselaar, L.; Roeh, S.; Wiechmann, T.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Schmidt, M. V.; Binder, E. B.: Extensive evaluation of DNA methylation of functional elements in the murine Fkbp5 locus using high-accuracy DNA methylation measurement via targeted bisulfite sequencing. EUROPEAN JOURNAL OF NEUROSCIENCE (2023)

Czamara, D.; Cruceanu, C.; Lahti-Pulkkinen, M.; Dieckmann, L.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Sammallahti, S.; Kajantie, E.; Laivuori, H. et al.; Lahti, J.; Raikkonen, K.; Binder, E. B.: Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (19), 11448 (2022)

Cruceanu, C.; Dony, L.; Krontira, A. C.; Fischer, D. S.; Roeh, S.; Di Giaimo, R.; Kyrousi, C.; Kaspar, L.; Arloth, J.; Czamara, D. et al.; Gerstner, N.; Martinelli, S.; Wehner, S.; Breen, M. S.; Koedel, M.; Sauer, S.; Sportelli, V.; Rex-Haffner, M.; Cappello, S.; Theis, F. J.; Binder, E. B.: Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study. AMERICAN JOURNAL OF PSYCHIATRY 179 (5), pp. 375 - 387 (2022)

Gerstner, N.; Krontira, A. C.; Cruceanu, C.; Roeh, S.; Puetz, B.; Sauer, S.; Rex-Haffner, M.; Schmidt, M. V.; Binder, E. B.; Knauer-Arloth, J.: DiffBrainNet: Differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regions. NEUROBIOLOGY OF STRESS 21, 100496 (2022)

Womersley, J. S.; Roeh, S.; Martin, L.; Ahmed-Leitao, F.; Sauer, S.; Rex-Haffner, M.; Hemmings, S. M. J.; Binder, E. B.; Seedat, S.: FKBP5 intron 7 methylation is associated with higher anxiety proneness and smaller right thalamus volume in adolescents. BRAIN STRUCTURE & FUNCTION 227 (8), pp. 2809 - 2820 (2022)

Martins, J.; Czamara, D.; Sauer, S.; Rex-Haffner, M.; Dittrich, K.; Doerr, P.; de Punder, K.; Overfeld, J.; Knop, A.; Dammering, F. et al.; Entringer, S.; Winter, S. M.; Buss, C.; Heim, C.; Binder, E. B.: Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress. NEUROBIOLOGY OF STRESS 15, 100336 (2021)

Wiechmann, T.; Roeh, S.; Sauer, S.; Czamara, D.; Arloth, J.; Koedel, M.; Beintner, M.; Knop, L.; Menke, A.; Binder, E. B. et al.; Provencal, N.: Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus. CLINICAL EPIGENETICS 11, 83 (2019)

Roeh, S.; Wiechmann, T.; Sauer, S.; Ködel, M.; Binder, E. B.; Provencal, N.: HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequencing. EPIGENETICS & CHROMATIN 11, 39 (2018)

Yusupov, N.; Dieckmann, L.; Erhart, M.; Sauer, S.; Rex-Haffner, M.; Kopf-Beck, J.; Brueckl, T.; Czamara, D.; Binder, E.: Transdiagnostic Evaluation of Epigenetic Age Acceleration and Burden of Psychiatric Disorders. In BIOLOGICAL PSYCHIATRY, 93 (9), p. S166 - S166. (2023)