Publications of Mathias V. Schmidt

Zimmermann, C. A.; Arloth, J.; Santarelli, S.; Loeschner, A.; Weber, P.; Schmidt, M. V.; Spengler, D.; Binder, E. B.: Stress dynamically regulates co-expression networks of glucocorticoid receptor-dependent MDD and SCZ risk genes. TRANSLATIONAL PSYCHIATRY 9, 41 (2019)

Gong, Q.; Su, Y.-A.; Wu, C.; Si, T.-M.; Deussing, J. M.; Schmidt, M. V.; Wang, X.-D.: Chronic Stress Reduces Nectin-1 mRNA Levels and Disrupts Dendritic Spine Plasticity in the Adult Mouse Perirhinal Cortex. FRONTIERS IN CELLULAR NEUROSCIENCE 12, 67 (2018)

Dedic, N.; Kühne, C.; Jakovcevski, M.; Hartmann, J.; Genewsky, A. J.; Gomes, K. S.; Anderzhanova, E.; Pöhlmann, M. L.; Chang, S.; Kolarz, A. et al.; Vogl, A. M.; Dine, J.; Metzger, M. W.; Schmid, B.; Almada, R. C.; Ressler, K. J.; Wotjak, C. T.; Grinevich, V.; Chen, A.; Schmidt, M. V.; Wurst, W.; Refojo, D.; Deussing, J. M.: Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety. NATURE NEUROSCIENCE 21 (6), pp. 803 - 807 (2018)

Dedic, N.; Poehlmann, M. L.; Richter, J. S.; Mehta, D.; Czamara, D.; Metzger, M. W.; Dine, J.; Bedenk, B. T.; Hartmann, J.; Wagner, K. V. et al.; Jurik, A.; Almli, L. M.; Lori, A.; Moosmang, S.; Hofmann, F.; Wotjak, C. T.; Rammes, G.; Eder, M.; Chen, A.; Ressler, K. J.; Wurst, W.; Schmidt, M. V.; Binder, E. B.; Deussing, J. M.: Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. MOLECULAR PSYCHIATRY 23 (3), pp. 533 - 543 (2018)

Emeny, R. T.; Baumert, J.; Zannas, A. S.; Kunze, S.; Wahl, S.; Iurato, S.; Arloth, J.; Erhardt, A.; Balsevich, G.; Schmidt, M. V. et al.; Weber, P.; Kretschmer, A.; Pfeiffer, L.; Kruse, J.; Strauch, K.; Roden, M.; Herder, C.; Koenig, W.; Gieger, C.; Waldenberger, M.; Peters, A.; Binder, E. B.; Ladwig, K.-H.: Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model. NEUROPSYCHOPHARMACOLOGY 43 (2), pp. 342 - 353 (2018)

Engel, M.; Eggert, C.; Kaplick, P. M.; Eder, M.; Röh, S.; Tietze, L.; Namendorf, C.; Arloth, J.; Weber, P.; Rex-Haffner, M. et al.; Geula, S.; Jakovcevski, M.; Hanna, J. H.; Leshkowitz, D.; Uhr, M.; Wotjak, C. T.; Schmidt, M. V.; Deussing, J. M.; Binder, E. B.; Chen, A.: The Role of m⁶A/m-RNA Methylation in Stress Response Regulation. NEURON 99 (2), pp. 389 - 403 (2018)

Maiaru, M.; Morgan, O. B.; Mao, T.; Breitsamer, M.; Bamber, H.; Pöhlmann, M.; Schmidt, M. V.; Winter, G.; Hausch, F.; Geranton, S. M.: The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes. PAIN 159 (7), pp. 1224 - 1234 (2018)

Masana, M.; Westerholz, S.; Kretzschmar, A.; Treccani, G.; Liebl, C.; Santarelli, S.; Dournes, C.; Popoli, M.; Schmidt, M. V.; Rein, T. et al.; Müller, M. B.: Expression and glucocorticoid-dependent regulation of the stress-inducible protein DRR1 in the mouse adult brain. Brain Structure & Function 223 (9), pp. 4039 - 4052 (2018)

Pillai, A. G.; Arp, M.; Velzing, E.; Lesuis, S. L.; Schmidt, M. V.; Holsboer, F.; Joels, M.; Krugers, H. J.: Early life stress determines the effects of glucocorticoids and stress on hippocampal function: Electrophysiological and behavioral evidence respectively. NEUROPHARMACOLOGY 133, pp. 307 - 318 (2018)

Pöhlmann, M. L.; Häusl, A. S.; Harbich, D.; Balsevich, G.; Engelhardt, C.; Feng, X.; Breitsamer, M.; Hausch, F.; Winter, G.; Schmidt, M. V.: Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs. FRONTIERS IN BEHAVIORAL NEUROSCIENCE 12, 262 (2018)

Hartmann, J.; Dedic, N.; Pöhlmann, M. L.; Häusl, A.; Karst, H.; Engelhardt, C.; Westerholz, S.; Wagner, K. V.; Labermaier, C.; Hoeijmakers, L. et al.; Kertokarijo, M.; Chen, A.; Joeels, M.; Deussing, J. M.; Schmidt, M. V.: Forebrain glutamatergic, but not GABAergic, neurons mediate anxiogenic effects of the glucocorticoid receptor. MOLECULAR PSYCHIATRY 22 (3), pp. 466 - 475 (2017)

Balsevich, G.; Häusl, A. S.; Meyer, C. W.; Karamihalev, S.; Feng, X.; Pöhlmann, M.; Dournes, C.; Uribe-Marino, A.; Santarelli, S.; Labermaier, C. et al.; Hafner, K.; Mao, T.; Breitsamer, M.; Theodoropoulou, M.; Namendorf, C.; Uhr, M.; Páez-Pereda, M.; Winter, G.; Hausch, F.; Chen, A.; Tschoep, M. H.; Rein, T.; Gassen, N. C.; Schmidt, M. V.: Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function. NATURE COMMUNICATIONS 8, 1725 (2017)

Carrillo-Roa, T.; Labermaier, C.; Weber, P.; Herzog, D. P.; Lareau, C.; Santarelli, S.; Wagner, K. V.; Rex-Haffner, M.; Harbich, D.; Scharf, S. H. et al.; Nemeroff, C. B.; Dunlop, B. W.; Craighead, W. E.; Mayberg, H. S.; Schmidt, M. V.; Uhr, M.; Holsboer, F.; Sillaber, I.; Binder, E. B.; Müller, M. B.: Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. PLOS BIOLOGY 15 (12), e2002690 (2017)

Li, J.-T.; Xie, X.-M.; Yu, J.-Y.; Sun, Y.-X.; Liao, X.-M.; Wang, X.-X.; Su, Y.-A.; Liu, Y.-J.; Schmidt, M. V.; Wang, X.-D. et al.; Si, T.-M.: Suppressed Calbindin Levels in Hippocampal Excitatory Neurons Mediate Stress-Induced Memory Loss. CELL REPORTS 21 (4), pp. 891 - 900 (2017)

Metzger, M. W.; Walser, S. M.; Dedic, N.; Aprile-Garcia, F.; Jakubcakova, V.; Adamczyk, M.; Webb, K. J.; Uhr, M.; Refojo, D.; Schmidt, M. V. et al.; Friess, E.; Steiger, A.; Kimura, M.; Chen, A.; Holsboer, F.; Arzt, E.; Wurst, W.; Deussing, J. M.: Heterozygosity for the Mood Disorder-Associated Variant Gln460Arg Alters P2X7 Receptor Function and Sleep Quality. JOURNAL OF NEUROSCIENCE 37 (48), pp. 11688 - 11700 (2017)

Santarelli, S.; Zimmermann, C.; Kalideris, G.; Lesuis, S. L.; Arloth, J.; Uribe, A.; Dournes, C.; Balsevich, G.; Hartmann, J.; Masana, M. et al.; Binder, E. B.; Spengler, D.; Schmidt, M. V.: An adverse early life environment can enhance stress resilience in adulthood. Psychoneuroendocrinology 78, pp. 213 - 221 (2017)

Wang, X.-X.; Li, J.-T.; Xie, X.-M.; Gu, Y.; Si, T.-M.; Schmidt, M. V.; Wang, X.-D.: Nectin-3 modulates the structural plasticity of dentate granule cells and long-term memory. TRANSLATIONAL PSYCHIATRY 7, e1228 (2017)

Uribe-Marino, A.; Gassen, N. C.; Wiesbeck, M. F.; Balsevich, G.; Santarelli, S.; Solfrank, B.; Dournes, C.; Fries, G. R.; Masana, M.; Labermaier, C. et al.; Wang, X.-D.; Hafner, K.; Schmid, B.; Rein, T.; Chen, A.; Deussing, J. M.; Schmidt, M. V.: Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction. BIOLOGICAL PSYCHIATRY 80 (10), pp. 743 - 753 (2016)

Gassen, N. C.; Hartmann, J.; Zannas, A. S.; Kretzschmar, A.; Zschocke, J.; Maccarrone, G.; Hafner, K.; Zellner, A.; Kollmannsberger, L. K.; Wag, K. V. et al.; Mehta, D.; Kloiber, S.; Turck, C. W.; Lucae, S.; Chrousos, G. P.; Holsboer, F.; Binder, E. B.; Ising, M.; Schmidt, M. V.; Rein, T.: FKBP51 inhibits GSK3 beta and augments the effects of distinct psychotropic medications. MOLECULAR PSYCHIATRY 21 (2), pp. 277 - 289 (2016)

Santarelli, S.; Wagner, K. V.; Labermaier, C.; Uribe, A.; Dournes, C.; Balsevich, G.; Hartmann, J.; Masana, M.; Holsboer, F.; Chen, A. et al.; Müller, M. B.; Schmidt, M. V.: SLC6A15, a novel stress vulnerability candidate, modulates anxiety and depressive-like behavior: involvement of the glutamatergic system. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS 19 (1), pp. 83 - 90 (2016)