Publikationen von D. Spengler

Barz, T.; Hoffmann, A.; Panhuysen, M.; Spengler, D.: Peroxisome proliferator-activated receptor gamma is a Zac target gene mediating Zac antiproliferation. Cancer Research 66 (24), S. 11975 - 11982 (2006)

Hoffmann, A.; Barz, T.; Spengler, D.: Multitasking C2H2 zinc fingers link zac DNA binding to coordinated regulation of p300-histone acetyltransferase activity. Molecular and Cellular Biology 26 (14), S. 5544 - 5557 (2006)

Murgatroyd, C.; Bilko, D.; Spengler, D.: Isolation of high-quality DNA for genotyping from feces of rodents. Analytical Biochemistry 348 (1), S. 160 - 162 (2006)

Murgatroyd, C.; Wigger, A.; Frank, E.; Singewald, N.; Bunck, M.; Holsboer, F.; Landgraf, R.; Spengler, D.: Impaired repression at a vasopressin promoter polymorphism underlies overexpression of vasopressin in a rat model of trait anxiety. Journal of Neuroscience 24 (35), S. 7762 - 7770 (2004)

Murgatroyd, C.; Wigger, A.; Spengler, D.; Landgraf, R.: Molecular-genetic dissection of anxiety/depression: From HAB phenotype to functional SNP. Pharmacopsychiatry 36 (5), S. 250 - 251 (2003)

Schmidt, P.; Holsboer, F.; Spengler, D.: β₂-adrenergic receptors potentiate glucocorticoid receptor transactivation via G protein β_γ-subunits and the phosphoinositide 3-kinase pathway. Molecular Endocrinology 15, S. 553 - 564 (2001)

Pagotto, U.; Arzberger, T.; Theodoropoulou, M.; Grübler, Y.; Pantaloni, C.; Saeger, W.; Losa, M.; Journot, L.; Stalla, G. K.; Spengler, D.: The expression of the antiproliferative gene ZAC is lost or highly reduced in nonfunctioning pituitary adenomas. Cancer Research 60, S. 6794 - 6799 (2000)

Bilanges, B.; Varrault, A.; Basyuk, E.; Rodriguez, C.; Mazumdar, A.; Pantaloni, C.; Bockaert, J.; Theillet, C.; Spengler, D.; Journot, L.: Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors. Oncogene 18, S. 3979 - 3988 (1999)

Ciani, E.; Hoffmann, A.; Schmidt, P.; Journot, L.; Spengler, D.: Induction of the PAC 1-R (PACAP-type I receptor) gene by p53 and Zac. Molecular Brain Research 69, S. 290 - 294 (1999)

Pagotto, U.; Arzberger, T.; Ciani, E.; Lezoualc`h, F.; Pilon, C.; Journot, L.; Spengler, D.; Stalla, G. K.: Inhibition of Zac 1, a new gene differentially expressed in the anterior pituitary, increases cell proliferation. Endocrinology 140, S. 987 - 996 (1999)

Hoffmann, A.; Ciani, E.; Houssami, S.; Brabet, P.; Journot, L.; Spengler, D.: Induction of type I PACAP receptor by the new zinc finger protein Zac1 and p53. Annals New York Academy of Sciences 865, S. 49 - 58 (1998)

Varrault, A.; Ciani, E.; Apiou, F.; Bilanges, B.; Hoffmann, A.; Pantaloni, C.; Bockaert, J.; Spengler, D.; Journot, L.: hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer. Proceedings of the National Academy of Sciences USA 95, S. 8835 - 8840 (1998)

Hoffmann, A.; Ciani, E.; Houssami, S.; Brabet, P.; Journot, L.; Spengler, D.: Induction of type IPACAP receptor expression by the new zinc finger protein Zac1 and p53. Regulatory Peptides 71, S. 114 - 114 (1997)

Hoffmann, A.; Villaba, N.; Journot, L.; Spengler, D.: A novel tetracycline-dependent expression vector with low basal expression and potent regulatory properties in various mammalian cell lines. Nucleic Acids Research 25, S. 1078 - 1079 (1997)

Spengler, D.; Villaba, M.; Hoffman, A.; Pantaloni, C.; Houssami, S.; Bockaert, J.; Journot, L.: Regulation of apoptosis and cell cycle arrest by Zac 1, a novel zinc finger protein expressed in the pituitary gland and the brain. EMBO Journal 16, S. 2814 - 2825 (1997)

Rupprecht, R.; Arriza, J. L.; Spengler, D.; Reul, J. M. H. M.; Evans, R. M.; Holsboer, F.; Damm, K.: Transactivation and synergistic properties of the mineralocorticoid receptor: relationship to the glucocorticoid receptor. Molecular Endocrinology 7, S. 597 - 603 (1993)

Rupprecht, R.; Reul, J. M. H. M.; van Steensel, B.; Spengler, D.; Söder, M.; Berning, B.; Holsboer, F.: Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands. European Journal of Pharmacology. Molecular Pharmacology Section 247, S. 269 - 276 (1993)

Spengler, D.; Waeber, C.; Pantaloni, C.; Holsboer, F.; Seeburg, P. H.; Bockaert, J.; Journot, L.: Differential signal transduction pattern of five splice variants of the PACAP receptor. Nature 365, S. 170 - 175 (1993)

Steiger, A.; Rupprecht, R.; Spengler, D.; Guldner, J.; Hemmeter, U.; Rothe, B.; Damm, K.; Holsboer, F.: Functional properties of deoxycorticosterone and spironolactone: Molecular characterization and effects on sleep endocrine activity. Journal of Psychiatric Research 27, S. 275 - 284 (1993)

Holsboer, F.; Spengler, D.; Heuser, I.: The role of corticotropin-releasing hormone in the pathogenesis of Cushing`s disease, anorexia nervosa, alcoholism, affective disorders and dementia. Progress in Brain Research 93, S. 385 - 417 (1992)