Publikationen von Maik Ködel

Dony, L.; Krontira, A. C.; Kaspar, L.; Ahmad, R.; Demirel , I. S.; Grochowicz, M.; Schafer, T.; Begum, F.; Sportelli, V.; Raimundo, C. et al.; Ködel, M.; Labeur, M.; Cappello, S.; Theis fabian, F. J.; Cruceanu, C.; Binder, E. B.: Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids. Science advances 11 (7), S. eadn8631 - eadn8631 (2025)

Gerstner, N.; Frohlich, A. S.; Matosin, N.; Gagliardi , M.; Cruceanu, C.; Kodel, M.; Rex-Haffner, M.; Tu, X.; Mostafavi, S.; Ziller, M. J. et al.; Binder, E. B.; Knauer-Arloth, J.: Contrasting genetic predisposition and diagnosis in psychiatric disorders: A multi-omic single-nucleus analysis of the human OFC. Science advances 11 (10), eadq2290 (2025)

Hagenberg, J.; Brueckl, T. M.; Erhart, M.; Kopf-Beck, J.; Koedel, M.; Rehawi, G.; Roeh-Karamihalev, S.; Sauer, S.; Yusupov, N.; Rex-Haffner, M. et al.; Spoormaker, V. I.; Saemann, P. G.; Binder, E. B.; Knauer-Arloth, J.: Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation. BRAIN BEHAVIOR AND IMMUNITY 123, S. 353 - 369 (2025)

Froehlich, A. S.; Gerstner, N.; Gagliardi, M.; Ködel, M.; Yusupov, N.; Matosin, N.; Czamara, D.; Sauer, S.; Roeh, S.; Murek, V. et al.; Chatzinakos, C.; Daskalakis, N. P.; Knauer-Arloth, J.; Ziller, M. J.; Binder, E. B.: Single-nucleus transcriptomic profiling of human orbitofrontal cortex reveals convergent effects of aging and psychiatric disease. NATURE NEUROSCIENCE 27, S. 2021 - 2032 (2024)

Krontira, A. C.; Cruceanu, C.; Dony, L.; Kyrousi, C.; Link, M.-H.; Rek, N.; Pöhlchen, D.; Raimundo, C.; Penner-Goeke, S.; Schowe, A. et al.; Czamara, D.; Lahti-Pulkkinen, M.; Sammallahti, S.; Wolford, E.; Heinonen, K.; Roeh, S.; Sportelli, V.; Woelfel, B.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Raikkonen, K.; Labeur, M.; Cappello, S.; Binder, E. B.: Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression. NEURON 112 (9), S. 1426 - 1443.e11 (2024)

Martinelli, S.; Hafner, K.; Ködel, M.; Knauer-Arloth, J.; Gassen, N. C.; Binder, E. B.: Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted Therapies. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 25 (22), 12318 (2024)

Yusupov, N.; Roeh, S.; Sotillos Elliott, L.; Chang, S.; Loganathan, S.; Urbina Trevino, L.; Fröhlich, A. S.; Sauer, S.; Ködel, M.; Matosin, N. et al.; Czamara, D.; Deussing, J. M.; Binder, E. B.: DNA methylation patterns of FKBP5 regulatory regions in brain and blood of humanized mice and humans. MOLECULAR PSYCHIATRY (2024)

Kuehnel, A.; Hagenberg, J.; Knauer-Arloth, J.; Koedel, M.; Czisch, M.; Saemann, P. G.; Binder, E. B.; Kroemer, N. B.: Stress-induced brain responses are associated with BMI in women. COMMUNICATIONS BIOLOGY 6 (1), 1031 (2023)

Matosin, N.; Arloth, J.; Czamara, D.; Edmond, K. Z.; Maitra, M.; Froehlich, A. S.; Martinelli, S.; Kaul, D.; Bartlett, R.; Curry, A. R. et al.; Gassen, N. C.; Hafner, K.; Mueller, N. S.; Worf, K.; Rehawi, G.; Nagy, C.; Halldorsdottir, T.; Cruceanu, C.; Gagliardi, M.; Gerstner, N.; Ködel, M.; Murek, V.; Ziller, M. J.; Scarr, E.; Tao, R.; Jaffe, A. E.; Arzberger, T.; Falkai, P.; Kleinmann, J. E.; Weinberger, D. R.; Mechawar, N.; Schmitt, A.; Dean, B.; Turecki, G.; Hyde, T. M.; Binder, E. B.: Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. ACTA NEUROPATHOLOGICA 145 (4), S. 439 - 459 (2023)

Penner-Goeke, S.; Bothe, M.; Rek, N.; Kreitmaier, P.; Poehlchen, D.; Kühnel, A.; Glaser, L. V.; Kaya, E.; Krontira, A.; Roeh, S. et al.; Czamara, D.; Ködel, M.; Monteserin-Garcia, J.; Diener, L.; Woelfel, B.; Sauer, S.; Rummel, C.; Riesenberg, S.; Arloth-Knauer, J.; Ziller, M.; Labeur, M.; Meijsing, S.; Binder, E. B.: High- throughput screening of glucocorticoid- induced enhancer activity reveals mechanisms of stress- related psychiatric disorders. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 (49), e2305773120 (2023)

Yusupov, N.; van Doeselaar, L.; Roeh, S.; Wiechmann, T.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Schmidt, M. V.; Binder, E. B.: Extensive evaluation of DNA methylation of functional elements in the murine Fkbp5 locus using high-accuracy DNA methylation measurement via targeted bisulfite sequencing. EUROPEAN JOURNAL OF NEUROSCIENCE (2023)

Czamara, D.; Cruceanu, C.; Lahti-Pulkkinen, M.; Dieckmann, L.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Sammallahti, S.; Kajantie, E.; Laivuori, H. et al.; Lahti, J.; Raikkonen, K.; Binder, E. B.: Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (19), 11448 (2022)

Cruceanu, C.; Dony, L.; Krontira, A. C.; Fischer, D. S.; Roeh, S.; Di Giaimo, R.; Kyrousi, C.; Kaspar, L.; Arloth, J.; Czamara, D. et al.; Gerstner, N.; Martinelli, S.; Wehner, S.; Breen, M. S.; Koedel, M.; Sauer, S.; Sportelli, V.; Rex-Haffner, M.; Cappello, S.; Theis, F. J.; Binder, E. B.: Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study. AMERICAN JOURNAL OF PSYCHIATRY 179 (5), S. 375 - 387 (2022)

Provencal, N.; Arloth, J.; Cattaneo, A.; Anacker, C.; Cattane, N.; Wiechmann, T.; Roeh, S.; Koedel, M.; Klengel, T.; Czamara, D. et al.; Mueller, N. S.; Lahti, J.; Raikkonen, K.; Pariante, C. M.; Binder, E. B.: Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (38), S. 23280 - 23285 (2020)

Wiechmann, T.; Roeh, S.; Sauer, S.; Czamara, D.; Arloth, J.; Koedel, M.; Beintner, M.; Knop, L.; Menke, A.; Binder, E. B. et al.; Provencal, N.: Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus. CLINICAL EPIGENETICS 11, 83 (2019)

Zannas, A. S.; Jia, M.; Hafner, K.; Baumert, J.; Wiechmann, T.; Pape, J. C.; Arloth, J.; Koedel, M.; Martinelli, S.; Roitman, M. et al.; Roeh, S.; Haehle, A.; Emeny, R. T.; Iurato, S.; Carrillo-Roa, T.; Lahti, J.; Raikkonen, K.; Eriksson, J. G.; Drake, A. J.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A. K.; Ressler, K. J.; Mueller-Myhsok, B.; Ladwig, K.-H.; Rein, T.; Gassen, N. C.; Binder, E. B.: Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (23), S. 11370 - 11379 (2019)

Roeh, S.; Wiechmann, T.; Sauer, S.; Ködel, M.; Binder, E. B.; Provencal, N.: HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequencing. EPIGENETICS & CHROMATIN 11, 39 (2018)

Cruceanu, C.; Roeh, S.; Wehner, S.; Martinelli, S.; Koedel, M.; Di Giaimo, R.; Cappello, S.; Binder, E.: Investigation of Prenatal Stress in the Cerebral Organoid Model: A Focus on Cell-Type Specific Responses Following Glucocorticoid Exposure. 73rd Annual Scientific Convention and Meeting, Annual Meeting of the Society of Biological Psychiatry (SOBP), New York, NY, 10. Mai 2018 - 12. Mai 2018. Biological Psychiatry 83 (9, Suppl.), 192, S. S77 - S77 (2018)

Cruceanu, C.; Roeh, S.; Martinelli, S.; Koedel, M.; Di Giaimo, R.; Cappello, S.; Binder, E.: Investigation of Prenatal Stress in the Cerebral Organoid Model: A Focus on Cell-Type Specific Responses Following Glucocorticoid Exposure. 56th Annual Meeting of the American College of Neuropsychopharmacology (ACNP), Palm Springs, CA, 03. Dezember 2017 - 07. Dezember 2017. NEUROPSYCHOPHARMACOLOGY 42, W158, S. S576 - S576 (2017)

Zannas, A. S.; Gassen, N. C.; Jia, M.; Baumert, J.; Hafner, K.; Ködel, M.; Haehle, A.; Iurato, S.; Carrillo-Roa, T.; Emeny, R. T. et al.; Lahti, J.; Raikkönen, K.; Eriksson, J.; Drake, A.; Waldenberger, M.; Wahl, S.; Kunze, S.; Lucae, S.; Bradley, B.; Gieger, C.; Hausch, F.; Smith, A. K.; Ressler, K. J.; Ludwig, K.-H.; Müller-Myhsok, B.; Rein, T.; Binder, E. B.: Aging- and stress-related epigenetic disinhibition of FKBP5 contributes to NF-κB-driven inflammation and cardiovascular risk. Conference of the World-Association-for-Stress-Related-and-Anxiety-Disorders (WASAD), Würzburg, Germany, 14. September 2017 - 16. September 2017. JOURNAL OF NEURAL TRANSMISSION 124 (10), S. 1292 - 1292 (2017)